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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDC
All Species:
45.76
Human Site:
Y79
Identified Species:
77.44
UniProt:
P20711
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20711
NP_000781.1
480
53894
Y79
H
S
P
Y
F
F
A
Y
F
P
T
A
S
S
Y
Chimpanzee
Pan troglodytes
Q5IS68
594
66879
F154
L
L
E
G
M
E
G
F
N
L
E
L
S
D
H
Rhesus Macaque
Macaca mulatta
XP_001082132
480
53813
Y79
H
S
P
Y
F
F
A
Y
F
P
T
A
S
S
Y
Dog
Lupus familis
XP_848285
480
53727
Y79
H
S
P
F
F
F
A
Y
F
P
S
A
N
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
O88533
480
53856
Y79
H
S
P
Y
F
F
A
Y
F
P
T
A
S
S
Y
Rat
Rattus norvegicus
P14173
480
54035
Y79
H
S
P
Y
F
F
A
Y
F
P
T
A
S
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419032
485
54932
Y79
H
S
P
Y
F
F
A
Y
F
P
S
A
S
S
F
Frog
Xenopus laevis
NP_001104211
485
54661
Y79
H
S
P
Y
F
F
A
Y
F
P
T
G
N
S
Y
Zebra Danio
Brachydanio rerio
NP_998507
480
54274
Y79
H
S
P
Y
F
Y
A
Y
F
P
T
A
H
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P05031
510
57269
Y114
H
S
P
K
F
H
A
Y
F
P
T
A
N
S
Y
Honey Bee
Apis mellifera
XP_394115
480
54685
Y79
H
S
P
K
F
H
A
Y
F
P
T
A
Q
S
Y
Nematode Worm
Caenorhab. elegans
P34751
905
101986
F421
S
H
P
N
F
H
S
F
Y
P
A
G
N
S
F
Sea Urchin
Strong. purpuratus
XP_798399
486
54852
Y80
N
H
P
N
F
H
A
Y
F
P
T
A
N
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RY79
490
54405
Y90
Q
S
P
S
F
F
A
Y
Y
P
S
N
S
S
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.5
96.8
87.2
N.A.
89.3
88.5
N.A.
N.A.
75.6
73.8
71.8
N.A.
56.4
61.4
22.7
58.4
Protein Similarity:
100
38.8
98.3
94.7
N.A.
96.2
96
N.A.
N.A.
88.2
87.6
86.4
N.A.
72.7
77.5
33.5
73.6
P-Site Identity:
100
6.6
100
80
N.A.
100
100
N.A.
N.A.
86.6
86.6
86.6
N.A.
80
80
26.6
60
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
93.3
N.A.
86.6
80
60
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
66.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
86
0
0
0
8
72
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
8
0
0
8
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
8
93
58
0
15
79
0
0
0
0
0
22
% F
% Gly:
0
0
0
8
0
0
8
0
0
0
0
15
0
0
0
% G
% His:
72
15
0
0
0
29
0
0
0
0
0
0
8
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
8
0
0
0
0
0
0
0
8
0
8
0
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
15
0
0
0
0
8
0
0
8
36
0
0
% N
% Pro:
0
0
93
0
0
0
0
0
0
93
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
79
0
8
0
0
8
0
0
0
22
0
50
93
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
65
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
50
0
8
0
86
15
0
0
0
0
0
65
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _