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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDC
All Species:
29.7
Human Site:
Y332
Identified Species:
50.26
UniProt:
P20711
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20711
NP_000781.1
480
53894
Y332
A
F
R
L
D
P
T
Y
L
K
H
S
H
Q
D
Chimpanzee
Pan troglodytes
Q5IS68
594
66879
Y434
C
N
Q
M
C
A
G
Y
L
F
Q
P
D
K
Q
Rhesus Macaque
Macaca mulatta
XP_001082132
480
53813
Y332
A
F
R
L
D
P
T
Y
L
K
H
S
H
Q
D
Dog
Lupus familis
XP_848285
480
53727
Y332
A
F
K
L
D
P
L
Y
L
K
H
N
H
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
O88533
480
53856
Y332
A
F
N
M
D
P
V
Y
L
K
H
S
H
Q
D
Rat
Rattus norvegicus
P14173
480
54035
Y332
A
F
N
M
D
P
V
Y
L
R
H
S
H
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419032
485
54932
Y332
A
F
K
L
E
P
L
Y
L
Q
H
H
H
Q
E
Frog
Xenopus laevis
NP_001104211
485
54661
Y332
A
F
K
M
D
P
V
Y
L
Q
Y
D
Q
Q
E
Zebra Danio
Brachydanio rerio
NP_998507
480
54274
Y332
A
F
K
M
E
P
L
Y
L
K
H
D
H
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P05031
510
57269
P364
V
N
A
F
N
V
D
P
L
Y
L
K
H
D
M
Honey Bee
Apis mellifera
XP_394115
480
54685
P330
I
N
A
F
N
M
D
P
L
Y
L
K
Y
D
I
Nematode Worm
Caenorhab. elegans
P34751
905
101986
L678
S
L
E
N
H
P
D
L
P
F
K
G
L
P
T
Sea Urchin
Strong. purpuratus
XP_798399
486
54852
R331
I
G
A
F
H
L
D
R
A
Y
F
K
H
H
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RY79
490
54405
F338
A
L
S
T
N
P
E
F
L
K
N
K
A
S
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.5
96.8
87.2
N.A.
89.3
88.5
N.A.
N.A.
75.6
73.8
71.8
N.A.
56.4
61.4
22.7
58.4
Protein Similarity:
100
38.8
98.3
94.7
N.A.
96.2
96
N.A.
N.A.
88.2
87.6
86.4
N.A.
72.7
77.5
33.5
73.6
P-Site Identity:
100
13.3
100
80
N.A.
80
73.3
N.A.
N.A.
60
46.6
60
N.A.
13.3
6.6
6.6
6.6
P-Site Similarity:
100
33.3
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
86.6
80
86.6
N.A.
20
20
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
66.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
65
0
22
0
0
8
0
0
8
0
0
0
8
0
0
% A
% Cys:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
43
0
29
0
0
0
0
15
8
15
36
% D
% Glu:
0
0
8
0
15
0
8
0
0
0
0
0
0
0
22
% E
% Phe:
0
58
0
22
0
0
0
8
0
15
8
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
15
0
0
0
0
0
50
8
65
8
8
% H
% Ile:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
29
0
0
0
0
0
0
43
8
29
0
8
0
% K
% Leu:
0
15
0
29
0
8
22
8
86
0
15
0
8
0
0
% L
% Met:
0
0
0
36
0
8
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
22
15
8
22
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
0
0
0
0
0
72
0
15
8
0
0
8
0
8
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
15
8
0
8
58
15
% Q
% Arg:
0
0
15
0
0
0
0
8
0
8
0
0
0
0
0
% R
% Ser:
8
0
8
0
0
0
0
0
0
0
0
29
0
8
0
% S
% Thr:
0
0
0
8
0
0
15
0
0
0
0
0
0
0
8
% T
% Val:
8
0
0
0
0
8
22
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
22
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _