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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDC
All Species:
44.55
Human Site:
Y20
Identified Species:
75.38
UniProt:
P20711
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20711
NP_000781.1
480
53894
Y20
M
V
D
Y
V
A
N
Y
M
E
G
I
E
G
R
Chimpanzee
Pan troglodytes
Q5IS68
594
66879
S82
N
L
L
S
C
E
N
S
D
R
D
A
R
F
R
Rhesus Macaque
Macaca mulatta
XP_001082132
480
53813
Y20
M
V
D
Y
V
A
N
Y
M
E
G
I
E
G
R
Dog
Lupus familis
XP_848285
480
53727
Y20
M
V
D
F
V
A
D
Y
L
E
G
I
E
G
R
Cat
Felis silvestris
Mouse
Mus musculus
O88533
480
53856
Y20
M
V
D
Y
I
A
D
Y
L
D
G
I
E
G
R
Rat
Rattus norvegicus
P14173
480
54035
Y20
M
V
D
Y
I
A
D
Y
L
D
G
I
E
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419032
485
54932
Y20
M
V
D
Y
V
A
D
Y
L
E
K
I
E
K
R
Frog
Xenopus laevis
NP_001104211
485
54661
Y20
M
V
D
Y
V
A
D
Y
L
E
Q
I
E
S
R
Zebra Danio
Brachydanio rerio
NP_998507
480
54274
Y20
M
V
D
Y
V
A
D
Y
I
E
N
I
E
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P05031
510
57269
Y55
M
V
D
F
I
A
E
Y
L
E
N
I
R
E
R
Honey Bee
Apis mellifera
XP_394115
480
54685
Y20
M
I
E
Y
I
I
N
Y
V
E
N
I
R
D
R
Nematode Worm
Caenorhab. elegans
P34751
905
101986
Q362
V
V
D
Y
L
M
K
Q
D
E
S
I
R
A
A
Sea Urchin
Strong. purpuratus
XP_798399
486
54852
Y21
M
V
D
Y
I
S
R
Y
Q
D
G
I
E
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RY79
490
54405
Y31
M
V
D
F
I
A
D
Y
Y
K
T
I
E
D
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.5
96.8
87.2
N.A.
89.3
88.5
N.A.
N.A.
75.6
73.8
71.8
N.A.
56.4
61.4
22.7
58.4
Protein Similarity:
100
38.8
98.3
94.7
N.A.
96.2
96
N.A.
N.A.
88.2
87.6
86.4
N.A.
72.7
77.5
33.5
73.6
P-Site Identity:
100
13.3
100
80
N.A.
73.3
73.3
N.A.
N.A.
73.3
73.3
73.3
N.A.
53.3
46.6
33.3
60
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
N.A.
86.6
86.6
86.6
N.A.
73.3
73.3
46.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
66.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
72
0
0
0
0
0
8
0
8
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
86
0
0
0
50
0
15
22
8
0
0
22
0
% D
% Glu:
0
0
8
0
0
8
8
0
0
65
0
0
72
8
0
% E
% Phe:
0
0
0
22
0
0
0
0
0
0
0
0
0
8
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
43
0
0
36
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
43
8
0
0
8
0
0
93
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
8
8
0
0
15
0
% K
% Leu:
0
8
8
0
8
0
0
0
43
0
0
0
0
0
0
% L
% Met:
86
0
0
0
0
8
0
0
15
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
29
0
0
0
22
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
8
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
8
0
0
29
0
86
% R
% Ser:
0
0
0
8
0
8
0
8
0
0
8
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
8
86
0
0
43
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
72
0
0
0
86
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _