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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDC
All Species:
16.36
Human Site:
S220
Identified Species:
27.69
UniProt:
P20711
Number Species:
13
Phosphosite Substitution
Charge Score:
0.46
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20711
NP_000781.1
480
53894
S220
G
N
F
A
M
R
A
S
A
L
Q
E
A
L
E
Chimpanzee
Pan troglodytes
Q5IS68
594
66879
D323
R
G
K
I
I
P
A
D
F
E
A
K
I
L
E
Rhesus Macaque
Macaca mulatta
XP_001082132
480
53813
S220
G
N
F
A
M
R
A
S
A
L
Q
E
A
L
E
Dog
Lupus familis
XP_848285
480
53727
S220
G
K
F
A
M
R
A
S
A
L
Q
E
A
L
E
Cat
Felis silvestris
Mouse
Mus musculus
O88533
480
53856
S220
G
N
F
S
M
R
A
S
A
L
R
E
A
L
E
Rat
Rattus norvegicus
P14173
480
54035
A220
G
N
Y
S
M
R
A
A
A
L
R
E
A
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419032
485
54932
S220
D
T
F
A
V
H
G
S
A
L
K
K
I
L
D
Frog
Xenopus laevis
NP_001104211
485
54661
Q220
E
K
F
V
A
R
G
Q
A
L
K
K
A
L
E
Zebra Danio
Brachydanio rerio
NP_998507
480
54274
D220
S
K
F
S
V
R
G
D
A
L
E
R
I
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P05031
510
57269
A255
N
H
R
M
R
G
A
A
L
E
K
A
I
E
Q
Honey Bee
Apis mellifera
XP_394115
480
54685
E220
S
K
Y
K
L
R
G
E
S
L
A
E
A
I
R
Nematode Worm
Caenorhab. elegans
P34751
905
101986
D565
Q
N
F
I
L
R
G
D
T
L
H
A
A
I
M
Sea Urchin
Strong. purpuratus
XP_798399
486
54852
D221
D
K
G
S
L
R
G
D
V
L
Q
K
A
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RY79
490
54405
E226
T
N
Y
A
L
R
P
E
S
L
Q
E
A
V
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.5
96.8
87.2
N.A.
89.3
88.5
N.A.
N.A.
75.6
73.8
71.8
N.A.
56.4
61.4
22.7
58.4
Protein Similarity:
100
38.8
98.3
94.7
N.A.
96.2
96
N.A.
N.A.
88.2
87.6
86.4
N.A.
72.7
77.5
33.5
73.6
P-Site Identity:
100
20
100
93.3
N.A.
86.6
73.3
N.A.
N.A.
40
46.6
33.3
N.A.
6.6
26.6
33.3
33.3
P-Site Similarity:
100
33.3
100
93.3
N.A.
100
100
N.A.
N.A.
66.6
60
60
N.A.
33.3
53.3
46.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
66.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
36
8
0
50
15
58
0
15
15
72
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
0
0
0
0
29
0
0
0
0
0
0
8
% D
% Glu:
8
0
0
0
0
0
0
15
0
15
8
50
0
8
58
% E
% Phe:
0
0
58
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
36
8
8
0
0
8
43
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
8
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
15
8
0
0
0
0
0
0
0
29
22
0
% I
% Lys:
0
36
8
8
0
0
0
0
0
0
22
29
0
0
8
% K
% Leu:
0
0
0
0
29
0
0
0
8
86
0
0
0
65
0
% L
% Met:
0
0
0
8
36
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
43
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
8
0
0
36
0
0
0
8
% Q
% Arg:
8
0
8
0
8
79
0
0
0
0
15
8
0
0
8
% R
% Ser:
15
0
0
29
0
0
0
36
15
0
0
0
0
0
8
% S
% Thr:
8
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
8
15
0
0
0
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
22
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _