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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDC All Species: 40
Human Site: S211 Identified Species: 67.69
UniProt: P20711 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20711 NP_000781.1 480 53894 S211 V K L K A I P S D G N F A M R
Chimpanzee Pan troglodytes Q5IS68 594 66879 N314 N V I L I K C N E R G K I I P
Rhesus Macaque Macaca mulatta XP_001082132 480 53813 S211 V K L K A I P S D G N F A M R
Dog Lupus familis XP_848285 480 53727 S211 V K L K A I P S D G K F A M R
Cat Felis silvestris
Mouse Mus musculus O88533 480 53856 S211 I K L K A V P S D G N F S M R
Rat Rattus norvegicus P14173 480 54035 S211 V K I K A I P S D G N Y S M R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419032 485 54932 S211 V K M K S V P S D D T F A V H
Frog Xenopus laevis NP_001104211 485 54661 S211 V R M K K I P S D E K F V A R
Zebra Danio Brachydanio rerio NP_998507 480 54274 T211 V R M K K I P T D S K F S V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P05031 510 57269 S246 V K L R S V Q S E N H R M R G
Honey Bee Apis mellifera XP_394115 480 54685 V211 V K F R L L E V D S K Y K L R
Nematode Worm Caenorhab. elegans P34751 905 101986 T556 V K M R V L P T D Q N F I L R
Sea Urchin Strong. purpuratus XP_798399 486 54852 T212 L R I R Q L A T D D K G S L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RY79 490 54405 S217 C R V L T T D S S T N Y A L R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.5 96.8 87.2 N.A. 89.3 88.5 N.A. N.A. 75.6 73.8 71.8 N.A. 56.4 61.4 22.7 58.4
Protein Similarity: 100 38.8 98.3 94.7 N.A. 96.2 96 N.A. N.A. 88.2 87.6 86.4 N.A. 72.7 77.5 33.5 73.6
P-Site Identity: 100 0 100 93.3 N.A. 80 80 N.A. N.A. 53.3 53.3 46.6 N.A. 26.6 26.6 46.6 13.3
P-Site Similarity: 100 26.6 100 93.3 N.A. 100 100 N.A. N.A. 80 66.6 80 N.A. 60 53.3 80 66.6
Percent
Protein Identity: N.A. N.A. N.A. 49.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 66.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 36 0 8 0 0 0 0 0 36 8 0 % A
% Cys: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 79 15 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 0 15 8 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 58 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 36 8 8 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % H
% Ile: 8 0 22 0 8 43 0 0 0 0 0 0 15 8 0 % I
% Lys: 0 65 0 58 15 8 0 0 0 0 36 8 8 0 0 % K
% Leu: 8 0 36 15 8 22 0 0 0 0 0 0 0 29 0 % L
% Met: 0 0 29 0 0 0 0 0 0 0 0 0 8 36 0 % M
% Asn: 8 0 0 0 0 0 0 8 0 8 43 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 65 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 8 0 8 0 0 8 0 0 0 0 0 % Q
% Arg: 0 29 0 29 0 0 0 0 0 8 0 8 0 8 79 % R
% Ser: 0 0 0 0 15 0 0 65 8 15 0 0 29 0 0 % S
% Thr: 0 0 0 0 8 8 0 22 0 8 8 0 0 0 0 % T
% Val: 72 8 8 0 8 22 0 8 0 0 0 0 8 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 22 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _