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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COX5A
All Species:
25.45
Human Site:
S45
Identified Species:
40
UniProt:
P20674
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20674
NP_004246.2
150
16762
S45
V
R
C
Y
S
H
G
S
Q
E
T
D
E
E
F
Chimpanzee
Pan troglodytes
B0VYX1
150
16630
S45
V
R
C
Y
S
H
G
S
Q
E
T
D
E
E
F
Rhesus Macaque
Macaca mulatta
Q53CF8
150
16651
S45
V
R
C
Y
S
H
G
S
H
E
T
D
E
E
F
Dog
Lupus familis
XP_853952
151
16625
S46
V
R
C
Y
S
H
G
S
H
E
T
D
E
E
F
Cat
Felis silvestris
Mouse
Mus musculus
P12787
146
16083
S41
I
R
C
Y
S
H
G
S
H
E
T
D
E
E
F
Rat
Rattus norvegicus
P11240
146
16111
S41
I
R
C
Y
S
H
G
S
H
E
T
D
E
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511903
376
41939
S271
A
R
C
Y
S
H
G
S
H
E
T
D
E
E
F
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085392
148
16448
K43
A
R
C
Y
S
H
A
K
H
E
S
D
E
E
F
Zebra Danio
Brachydanio rerio
XP_700576
172
19236
K67
V
R
C
Y
S
H
A
K
V
E
T
D
E
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94514
149
16604
F40
T
E
E
S
A
E
E
F
D
K
R
Y
E
K
Y
Honey Bee
Apis mellifera
XP_392368
152
17602
N43
Q
E
T
E
E
E
F
N
K
Q
Y
V
T
Y
L
Nematode Worm
Caenorhab. elegans
P55954
174
20092
W39
G
D
D
I
M
E
K
W
P
A
D
K
F
D
N
Sea Urchin
Strong. purpuratus
XP_784558
149
16879
E39
R
G
Y
S
A
K
V
E
E
T
D
E
Q
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P00427
148
17323
D45
R
K
Y
S
D
A
H
D
E
E
T
F
E
E
F
Red Bread Mold
Neurospora crassa
Q01359
148
16785
H44
S
R
F
R
S
E
H
H
E
E
T
F
E
E
F
Conservation
Percent
Protein Identity:
100
98
96
86.7
N.A.
86
85.3
N.A.
35.6
N.A.
78
60.4
N.A.
48.6
48
36.7
59.3
Protein Similarity:
100
98
96.6
90
N.A.
88.6
88
N.A.
36.7
N.A.
85.3
70.9
N.A.
64
67.7
54
70.6
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
86.6
N.A.
66.6
80
N.A.
6.6
0
0
0
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
86.6
N.A.
73.3
80
N.A.
33.3
20
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.3
32
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.6
48.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
14
7
14
0
0
7
0
0
0
0
0
% A
% Cys:
0
0
60
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
7
0
0
7
7
0
14
60
0
7
7
% D
% Glu:
0
14
7
7
7
27
7
7
20
74
0
7
80
74
0
% E
% Phe:
0
0
7
0
0
0
7
7
0
0
0
14
7
7
74
% F
% Gly:
7
7
0
0
0
0
47
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
60
14
7
40
0
0
0
0
0
0
% H
% Ile:
14
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
7
0
0
0
7
7
14
7
7
0
7
0
7
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
14
7
0
0
7
0
0
% Q
% Arg:
14
67
0
7
0
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
7
0
0
20
67
0
0
47
0
0
7
0
0
0
0
% S
% Thr:
7
0
7
0
0
0
0
0
0
7
67
0
7
0
0
% T
% Val:
34
0
0
0
0
0
7
0
7
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
14
60
0
0
0
0
0
0
7
7
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _