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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
M6PR
All Species:
19.7
Human Site:
T101
Identified Species:
39.39
UniProt:
P20645
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20645
NP_002346.1
277
30993
T101
N
K
S
N
G
K
E
T
V
V
G
R
L
N
E
Chimpanzee
Pan troglodytes
XP_001137994
244
27171
I93
S
G
A
G
L
V
Q
I
N
K
S
N
G
K
E
Rhesus Macaque
Macaca mulatta
XP_001113975
278
31085
T102
N
K
S
N
G
K
E
T
V
V
G
R
L
N
E
Dog
Lupus familis
XP_534894
396
43228
T220
N
K
S
N
G
K
E
T
V
V
G
R
L
N
E
Cat
Felis silvestris
Mouse
Mus musculus
P24668
278
31154
T102
N
K
S
N
D
K
E
T
V
V
G
R
I
N
E
Rat
Rattus norvegicus
Q6AY20
278
31077
T102
N
K
S
N
E
K
E
T
V
V
G
R
I
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514710
258
28364
S106
L
Y
D
L
S
F
E
S
S
V
G
Q
D
S
E
Chicken
Gallus gallus
XP_416477
298
33190
R108
L
E
P
L
S
Q
I
R
F
N
T
T
V
E
I
Frog
Xenopus laevis
NP_001080870
273
29899
G110
N
D
T
H
I
M
S
G
T
D
W
I
L
L
I
Zebra Danio
Brachydanio rerio
NP_998370
265
29164
D104
T
V
A
T
A
G
S
D
W
V
L
L
I
Y
E
Tiger Blowfish
Takifugu rubipres
NP_001033033
272
30118
N112
T
Q
A
I
G
E
S
N
W
V
F
L
T
Y
T
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784873
183
20114
K32
V
A
S
P
S
E
N
K
Y
L
E
L
I
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.7
98.9
66.4
N.A.
91.7
91
N.A.
54.1
52
59.2
48.7
42.9
N.A.
N.A.
N.A.
30.3
Protein Similarity:
100
87.7
99.2
68.6
N.A.
95.6
95.6
N.A.
63.9
63.7
72.9
66.7
59.9
N.A.
N.A.
N.A.
42.6
P-Site Identity:
100
6.6
100
100
N.A.
86.6
86.6
N.A.
26.6
0
13.3
13.3
13.3
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
100
100
N.A.
93.3
93.3
N.A.
46.6
20
26.6
26.6
33.3
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
25
0
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
9
0
0
9
0
9
0
0
9
0
0
% D
% Glu:
0
9
0
0
9
17
50
0
0
0
9
0
0
17
67
% E
% Phe:
0
0
0
0
0
9
0
0
9
0
9
0
0
0
0
% F
% Gly:
0
9
0
9
34
9
0
9
0
0
50
0
9
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
9
0
9
9
0
0
0
9
34
0
17
% I
% Lys:
0
42
0
0
0
42
0
9
0
9
0
0
0
9
0
% K
% Leu:
17
0
0
17
9
0
0
0
0
9
9
25
34
9
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
0
0
42
0
0
9
9
9
9
0
9
0
42
0
% N
% Pro:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
9
0
0
0
9
9
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
42
0
0
0
% R
% Ser:
9
0
50
0
25
0
25
9
9
0
9
0
0
9
0
% S
% Thr:
17
0
9
9
0
0
0
42
9
0
9
9
9
0
9
% T
% Val:
9
9
0
0
0
9
0
0
42
67
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
17
0
9
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
9
0
0
0
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _