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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPR2 All Species: 19.09
Human Site: S693 Identified Species: 38.18
UniProt: P20594 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20594 NP_003986.2 1047 117022 S693 W T A P E L L S G N P L P T T
Chimpanzee Pan troglodytes XP_001168194 1047 116964 S693 W T A P E L L S G N P L P T T
Rhesus Macaque Macaca mulatta XP_001085221 1047 116990 S693 W T A P E L L S G N P L P T T
Dog Lupus familis XP_531993 999 112273 E668 S F G I I L Q E I A L R S G P
Cat Felis silvestris
Mouse Mus musculus Q6VVW5 1047 117039 S693 W T A P E L L S G N P L P T T
Rat Rattus norvegicus P16067 1047 117109 S693 W T A P E L L S G N P L P T T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517544 743 84256 S447 Q R P Y F R P S I D R G Q L S
Chicken Gallus gallus
Frog Xenopus laevis NP_001084176 1082 122776 R729 W T A P E L L R M T R P P A P
Zebra Danio Brachydanio rerio XP_689479 1088 124806 I735 W T A P E L L I Y D R H P P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07553 1163 130896 L701 L C M A P E L L R D A Y R P G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09435 1137 128085 V733 V L R G S L S V S Q M E P S A
Sea Urchin Strong. purpuratus P16065 1125 126238 E742 R Q L W T S P E H L R Q E G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.8 89.1 N.A. 98.5 98.5 N.A. 64.5 N.A. 72.2 58.1 N.A. 32.5 N.A. 28.7 36.2
Protein Similarity: 100 99.9 100 90 N.A. 99.4 99.3 N.A. 67 N.A. 82.9 69.7 N.A. 49 N.A. 46.7 52.2
P-Site Identity: 100 100 100 6.6 N.A. 100 100 N.A. 6.6 N.A. 53.3 53.3 N.A. 6.6 N.A. 13.3 0
P-Site Similarity: 100 100 100 6.6 N.A. 100 100 N.A. 20 N.A. 53.3 60 N.A. 13.3 N.A. 20 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 59 9 0 0 0 0 0 9 9 0 0 9 9 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 25 0 0 0 0 0 % D
% Glu: 0 0 0 0 59 9 0 17 0 0 0 9 9 0 0 % E
% Phe: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 9 0 0 0 0 42 0 0 9 0 17 9 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % H
% Ile: 0 0 0 9 9 0 0 9 17 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 9 9 0 0 75 67 9 0 9 9 42 0 9 0 % L
% Met: 0 0 9 0 0 0 0 0 9 0 9 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 42 0 0 0 0 0 % N
% Pro: 0 0 9 59 9 0 17 0 0 0 42 9 67 17 17 % P
% Gln: 9 9 0 0 0 0 9 0 0 9 0 9 9 0 9 % Q
% Arg: 9 9 9 0 0 9 0 9 9 0 34 9 9 0 0 % R
% Ser: 9 0 0 0 9 9 9 50 9 0 0 0 9 9 17 % S
% Thr: 0 59 0 0 9 0 0 0 0 9 0 0 0 42 42 % T
% Val: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % V
% Trp: 59 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 9 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _