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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH3
All Species:
25.45
Human Site:
Y334
Identified Species:
50.91
UniProt:
P20585
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20585
NP_002430.2
1137
127440
Y334
S
R
K
L
T
A
L
Y
T
K
S
T
L
I
G
Chimpanzee
Pan troglodytes
XP_526872
653
74467
Rhesus Macaque
Macaca mulatta
XP_001110439
1124
126700
Y322
S
R
K
L
T
A
L
Y
T
K
S
T
L
I
G
Dog
Lupus familis
XP_536307
1124
126796
Y323
S
R
K
L
T
A
L
Y
T
K
S
T
L
I
G
Cat
Felis silvestris
Mouse
Mus musculus
P13705
1091
123056
Y292
S
R
K
L
T
A
L
Y
T
K
S
T
L
I
G
Rat
Rattus norvegicus
XP_001065837
1105
124697
Y292
S
R
K
L
T
A
L
Y
T
K
S
T
L
I
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512218
1058
119728
Q301
L
L
C
I
C
E
N
Q
N
Q
E
N
V
K
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103184
1083
121769
Y293
S
R
Q
L
H
A
L
Y
T
K
S
T
L
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193092
988
109454
F250
S
I
P
T
H
R
L
F
V
H
V
R
R
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65607
1081
119348
I292
R
S
G
L
E
A
V
I
L
S
L
S
P
A
E
Baker's Yeast
Sacchar. cerevisiae
P25336
1018
116515
W279
L
G
D
T
N
S
I
W
A
L
S
R
D
V
H
Red Bread Mold
Neurospora crassa
Q7SD11
1145
125674
Y304
V
R
K
L
T
N
V
Y
T
K
G
T
Y
I
D
Conservation
Percent
Protein Identity:
100
54.1
95.6
83.1
N.A.
78.3
78.8
N.A.
71.5
N.A.
N.A.
50.4
N.A.
N.A.
N.A.
N.A.
40.8
Protein Similarity:
100
56.1
96.6
88.7
N.A.
86
86.2
N.A.
81.2
N.A.
N.A.
68.5
N.A.
N.A.
N.A.
N.A.
57.4
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
0
N.A.
N.A.
80
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
20
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.6
30.4
36.7
Protein Similarity:
N.A.
N.A.
N.A.
55.8
49.5
55.9
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
60
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
59
0
0
9
0
0
0
0
9
0
% A
% Cys:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
17
% D
% Glu:
0
0
0
0
9
9
0
0
0
0
9
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
0
0
0
0
0
0
0
9
0
0
0
50
% G
% His:
0
0
0
0
17
0
0
0
0
9
0
0
0
0
9
% H
% Ile:
0
9
0
9
0
0
9
9
0
0
0
0
0
50
0
% I
% Lys:
0
0
50
0
0
0
0
0
0
59
0
0
0
9
0
% K
% Leu:
17
9
0
67
0
0
59
0
9
9
9
0
50
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
9
9
0
9
0
0
9
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
9
0
0
0
0
9
0
9
0
0
0
0
0
% Q
% Arg:
9
59
0
0
0
9
0
0
0
0
0
17
9
0
0
% R
% Ser:
59
9
0
0
0
9
0
0
0
9
59
9
0
0
0
% S
% Thr:
0
0
0
17
50
0
0
0
59
0
0
59
0
0
0
% T
% Val:
9
0
0
0
0
0
17
0
9
0
9
0
9
17
9
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _