KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH3
All Species:
18.18
Human Site:
T581
Identified Species:
36.36
UniProt:
P20585
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20585
NP_002430.2
1137
127440
T581
R
K
L
K
K
W
V
T
Q
P
L
L
K
L
R
Chimpanzee
Pan troglodytes
XP_526872
653
74467
I144
I
E
R
G
L
C
S
I
Y
H
K
K
C
S
T
Rhesus Macaque
Macaca mulatta
XP_001110439
1124
126700
T569
R
K
L
K
K
W
V
T
Q
P
L
L
K
L
R
Dog
Lupus familis
XP_536307
1124
126796
V570
R
K
L
K
K
W
V
V
Q
P
L
L
K
L
R
Cat
Felis silvestris
Mouse
Mus musculus
P13705
1091
123056
T539
R
K
L
K
N
W
V
T
Q
P
L
L
K
L
R
Rat
Rattus norvegicus
XP_001065837
1105
124697
T539
R
K
L
K
K
W
V
T
Q
P
L
L
K
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512218
1058
119728
Y530
A
V
S
E
V
L
L
Y
E
S
S
M
F
G
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103184
1083
121769
S540
R
L
L
R
K
W
V
S
Q
P
L
K
S
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193092
988
109454
W479
G
K
R
Q
L
M
K
W
L
S
Q
P
L
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65607
1081
119348
L523
Y
L
V
L
S
S
V
L
T
A
M
S
R
S
S
Baker's Yeast
Sacchar. cerevisiae
P25336
1018
116515
N508
P
D
L
L
R
T
L
N
R
I
M
Y
G
T
T
Red Bread Mold
Neurospora crassa
Q7SD11
1145
125674
G546
R
L
L
R
K
W
I
G
R
P
L
L
D
Q
Q
Conservation
Percent
Protein Identity:
100
54.1
95.6
83.1
N.A.
78.3
78.8
N.A.
71.5
N.A.
N.A.
50.4
N.A.
N.A.
N.A.
N.A.
40.8
Protein Similarity:
100
56.1
96.6
88.7
N.A.
86
86.2
N.A.
81.2
N.A.
N.A.
68.5
N.A.
N.A.
N.A.
N.A.
57.4
P-Site Identity:
100
0
100
93.3
N.A.
93.3
100
N.A.
0
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
6.6
100
93.3
N.A.
93.3
100
N.A.
33.3
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.6
30.4
36.7
Protein Similarity:
N.A.
N.A.
N.A.
55.8
49.5
55.9
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
9
% D
% Glu:
0
9
0
9
0
0
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
9
0
0
9
0
0
0
9
0
0
0
0
9
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
9
9
0
9
0
0
0
0
9
% I
% Lys:
0
50
0
42
50
0
9
0
0
0
9
17
42
0
0
% K
% Leu:
0
25
67
17
17
9
17
9
9
0
59
50
9
42
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
17
9
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
59
0
9
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
50
0
9
0
0
9
17
% Q
% Arg:
59
0
17
17
9
0
0
0
17
0
0
0
9
0
42
% R
% Ser:
0
0
9
0
9
9
9
9
0
17
9
9
9
17
9
% S
% Thr:
0
0
0
0
0
9
0
34
9
0
0
0
0
17
17
% T
% Val:
0
9
9
0
9
0
59
9
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
59
0
9
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
9
9
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _