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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH3
All Species:
20.91
Human Site:
T556
Identified Species:
41.82
UniProt:
P20585
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20585
NP_002430.2
1137
127440
T556
Q
N
Q
T
D
M
K
T
K
G
S
L
L
W
V
Chimpanzee
Pan troglodytes
XP_526872
653
74467
S45
A
V
S
E
V
L
H
S
E
S
S
V
F
G
Q
Rhesus Macaque
Macaca mulatta
XP_001110439
1124
126700
T544
Q
N
Q
T
D
M
K
T
K
G
S
L
L
W
V
Dog
Lupus familis
XP_536307
1124
126796
T545
Q
N
Q
T
D
M
K
T
K
G
S
L
L
W
V
Cat
Felis silvestris
Mouse
Mus musculus
P13705
1091
123056
T514
Q
N
Q
T
D
M
K
T
K
G
S
L
L
W
V
Rat
Rattus norvegicus
XP_001065837
1105
124697
T514
Q
N
Q
T
D
M
K
T
R
G
S
L
L
W
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512218
1058
119728
K505
F
G
R
R
R
L
K
K
W
V
T
Q
P
L
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103184
1083
121769
V515
C
N
Q
T
T
G
S
V
K
G
S
L
L
W
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193092
988
109454
G454
I
F
Q
N
Q
V
D
G
S
E
K
G
T
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65607
1081
119348
S498
S
H
S
S
S
Q
L
S
S
E
L
V
E
E
G
Baker's Yeast
Sacchar. cerevisiae
P25336
1018
116515
E483
A
I
E
C
I
T
S
E
I
N
N
S
I
F
F
Red Bread Mold
Neurospora crassa
Q7SD11
1145
125674
E521
R
N
A
T
D
H
S
E
K
G
S
L
L
W
A
Conservation
Percent
Protein Identity:
100
54.1
95.6
83.1
N.A.
78.3
78.8
N.A.
71.5
N.A.
N.A.
50.4
N.A.
N.A.
N.A.
N.A.
40.8
Protein Similarity:
100
56.1
96.6
88.7
N.A.
86
86.2
N.A.
81.2
N.A.
N.A.
68.5
N.A.
N.A.
N.A.
N.A.
57.4
P-Site Identity:
100
6.6
100
100
N.A.
100
93.3
N.A.
6.6
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
33.3
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.6
30.4
36.7
Protein Similarity:
N.A.
N.A.
N.A.
55.8
49.5
55.9
P-Site Identity:
N.A.
N.A.
N.A.
0
0
60
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% A
% Cys:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
50
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
9
0
0
0
17
9
17
0
0
9
9
0
% E
% Phe:
9
9
0
0
0
0
0
0
0
0
0
0
9
9
9
% F
% Gly:
0
9
0
0
0
9
0
9
0
59
0
9
0
9
9
% G
% His:
0
9
0
0
0
9
9
0
0
0
0
0
0
0
0
% H
% Ile:
9
9
0
0
9
0
0
0
9
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
0
50
9
50
0
9
0
0
0
0
% K
% Leu:
0
0
0
0
0
17
9
0
0
0
9
59
59
17
17
% L
% Met:
0
0
0
0
0
42
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
59
0
9
0
0
0
0
0
9
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
42
0
59
0
9
9
0
0
0
0
0
9
0
0
9
% Q
% Arg:
9
0
9
9
9
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
9
0
17
9
9
0
25
17
17
9
67
9
0
0
0
% S
% Thr:
0
0
0
59
9
9
0
42
0
0
9
0
9
0
0
% T
% Val:
0
9
0
0
9
9
0
9
0
9
0
17
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
59
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _