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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH3
All Species:
4.85
Human Site:
T230
Identified Species:
9.7
UniProt:
P20585
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20585
NP_002430.2
1137
127440
T230
K
R
S
K
S
I
Y
T
P
L
E
L
Q
Y
I
Chimpanzee
Pan troglodytes
XP_526872
653
74467
Rhesus Macaque
Macaca mulatta
XP_001110439
1124
126700
T218
K
R
S
K
S
I
Y
T
P
L
E
L
Q
Y
I
Dog
Lupus familis
XP_536307
1124
126796
Y218
N
K
R
T
K
S
I
Y
T
P
L
E
L
Q
Y
Cat
Felis silvestris
Mouse
Mus musculus
P13705
1091
123056
L190
S
K
S
V
Y
T
P
L
E
L
Q
Y
L
D
M
Rat
Rattus norvegicus
XP_001065837
1105
124697
L190
S
K
S
I
Y
T
P
L
E
L
Q
Y
L
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512218
1058
119728
I199
I
A
A
R
E
L
N
I
Y
C
H
L
D
H
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103184
1083
121769
L191
T
K
T
I
Y
T
P
L
E
E
Q
Y
M
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193092
988
109454
N151
P
K
L
T
A
L
K
N
K
F
S
R
H
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65607
1081
119348
K191
Q
T
E
T
A
A
I
K
S
H
G
A
N
R
T
Baker's Yeast
Sacchar. cerevisiae
P25336
1018
116515
G180
L
H
I
K
L
V
P
G
K
L
T
I
D
E
S
Red Bread Mold
Neurospora crassa
Q7SD11
1145
125674
L205
R
K
H
M
D
T
L
L
I
V
E
V
G
Y
K
Conservation
Percent
Protein Identity:
100
54.1
95.6
83.1
N.A.
78.3
78.8
N.A.
71.5
N.A.
N.A.
50.4
N.A.
N.A.
N.A.
N.A.
40.8
Protein Similarity:
100
56.1
96.6
88.7
N.A.
86
86.2
N.A.
81.2
N.A.
N.A.
68.5
N.A.
N.A.
N.A.
N.A.
57.4
P-Site Identity:
100
0
100
0
N.A.
13.3
13.3
N.A.
6.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
0
100
6.6
N.A.
33.3
33.3
N.A.
33.3
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.6
30.4
36.7
Protein Similarity:
N.A.
N.A.
N.A.
55.8
49.5
55.9
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
17
9
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
0
0
0
17
17
0
% D
% Glu:
0
0
9
0
9
0
0
0
25
9
25
9
0
17
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
9
0
9
0
9
% G
% His:
0
9
9
0
0
0
0
0
0
9
9
0
9
9
0
% H
% Ile:
9
0
9
17
0
17
17
9
9
0
0
9
0
0
25
% I
% Lys:
17
50
0
25
9
0
9
9
17
0
0
0
0
0
9
% K
% Leu:
9
0
9
0
9
17
9
34
0
42
9
25
25
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
9
% M
% Asn:
9
0
0
0
0
0
9
9
0
0
0
0
9
0
9
% N
% Pro:
9
0
0
0
0
0
34
0
17
9
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
25
0
17
9
0
% Q
% Arg:
9
17
9
9
0
0
0
0
0
0
0
9
0
9
0
% R
% Ser:
17
0
34
0
17
9
0
0
9
0
9
0
0
9
9
% S
% Thr:
9
9
9
25
0
34
0
17
9
0
9
0
0
0
9
% T
% Val:
0
0
0
9
0
9
0
0
0
9
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
25
0
17
9
9
0
0
25
0
25
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _