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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH3
All Species:
14.24
Human Site:
T1054
Identified Species:
28.48
UniProt:
P20585
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20585
NP_002430.2
1137
127440
T1054
E
Q
V
P
D
F
V
T
F
L
Y
Q
I
T
R
Chimpanzee
Pan troglodytes
XP_526872
653
74467
G578
F
L
Y
Q
I
T
R
G
I
A
A
R
S
Y
G
Rhesus Macaque
Macaca mulatta
XP_001110439
1124
126700
F1042
Q
V
P
D
F
V
T
F
L
Y
Q
I
T
R
G
Dog
Lupus familis
XP_536307
1124
126796
F1043
P
V
P
D
F
V
T
F
L
Y
Q
I
T
R
G
Cat
Felis silvestris
Mouse
Mus musculus
P13705
1091
123056
T1008
E
Q
M
P
D
S
V
T
F
L
Y
Q
I
T
R
Rat
Rattus norvegicus
XP_001065837
1105
124697
T1012
E
Q
M
P
D
S
V
T
F
L
Y
Q
I
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512218
1058
119728
V982
D
E
Q
T
P
E
F
V
T
F
L
Y
Q
L
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103184
1083
121769
T1008
E
A
Q
P
E
F
I
T
F
L
Y
Q
L
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193092
988
109454
Y913
V
E
K
L
T
F
L
Y
Q
L
V
D
G
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65607
1081
119348
V975
V
T
Y
L
Y
K
L
V
R
G
L
C
S
R
S
Baker's Yeast
Sacchar. cerevisiae
P25336
1018
116515
Y942
W
M
S
V
I
F
L
Y
K
L
K
K
G
L
T
Red Bread Mold
Neurospora crassa
Q7SD11
1145
125674
M1040
T
S
M
D
D
D
A
M
E
V
D
G
D
G
D
Conservation
Percent
Protein Identity:
100
54.1
95.6
83.1
N.A.
78.3
78.8
N.A.
71.5
N.A.
N.A.
50.4
N.A.
N.A.
N.A.
N.A.
40.8
Protein Similarity:
100
56.1
96.6
88.7
N.A.
86
86.2
N.A.
81.2
N.A.
N.A.
68.5
N.A.
N.A.
N.A.
N.A.
57.4
P-Site Identity:
100
0
0
0
N.A.
86.6
86.6
N.A.
0
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
6.6
6.6
0
N.A.
93.3
93.3
N.A.
13.3
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.6
30.4
36.7
Protein Similarity:
N.A.
N.A.
N.A.
55.8
49.5
55.9
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
9
0
0
9
9
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
9
0
0
25
34
9
0
0
0
0
9
9
9
0
9
% D
% Glu:
34
17
0
0
9
9
0
0
9
0
0
0
0
0
9
% E
% Phe:
9
0
0
0
17
34
9
17
34
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
9
0
9
17
9
25
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
17
0
9
0
9
0
0
17
25
9
0
% I
% Lys:
0
0
9
0
0
9
0
0
9
0
9
9
0
0
0
% K
% Leu:
0
9
0
17
0
0
25
0
17
50
17
0
9
17
0
% L
% Met:
0
9
25
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
17
34
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
25
17
9
0
0
0
0
9
0
17
34
9
0
0
% Q
% Arg:
0
0
0
0
0
0
9
0
9
0
0
9
0
25
25
% R
% Ser:
0
9
9
0
0
17
0
0
0
0
0
0
17
0
9
% S
% Thr:
9
9
0
9
9
9
17
34
9
0
0
0
17
25
17
% T
% Val:
17
17
9
9
0
17
25
17
0
9
9
0
0
9
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
17
0
9
0
0
17
0
17
34
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _