KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH3
All Species:
16.97
Human Site:
S410
Identified Species:
33.94
UniProt:
P20585
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20585
NP_002430.2
1137
127440
S410
D
S
F
Q
D
S
A
S
R
S
E
L
E
T
R
Chimpanzee
Pan troglodytes
XP_526872
653
74467
Rhesus Macaque
Macaca mulatta
XP_001110439
1124
126700
S398
D
S
F
Q
D
S
A
S
R
S
E
L
E
T
R
Dog
Lupus familis
XP_536307
1124
126796
S399
D
S
F
Q
D
S
A
S
R
S
E
L
E
T
R
Cat
Felis silvestris
Mouse
Mus musculus
P13705
1091
123056
S368
D
C
F
Q
D
S
A
S
R
L
E
L
E
T
R
Rat
Rattus norvegicus
XP_001065837
1105
124697
S368
D
C
F
Q
D
S
A
S
R
L
E
L
E
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512218
1058
119728
L359
E
L
L
L
P
S
H
L
S
D
Q
S
E
K
C
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103184
1083
121769
L369
D
N
M
S
H
S
E
L
E
S
R
I
L
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193092
988
109454
G308
Y
D
S
F
H
D
N
G
H
L
S
E
L
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65607
1081
119348
A352
S
L
C
E
K
I
S
A
G
N
L
E
D
D
K
Baker's Yeast
Sacchar. cerevisiae
P25336
1018
116515
D337
I
E
V
L
V
N
T
D
D
L
P
L
H
V
A
Red Bread Mold
Neurospora crassa
Q7SD11
1145
125674
E375
E
D
G
F
M
R
R
E
I
E
T
R
L
L
H
Conservation
Percent
Protein Identity:
100
54.1
95.6
83.1
N.A.
78.3
78.8
N.A.
71.5
N.A.
N.A.
50.4
N.A.
N.A.
N.A.
N.A.
40.8
Protein Similarity:
100
56.1
96.6
88.7
N.A.
86
86.2
N.A.
81.2
N.A.
N.A.
68.5
N.A.
N.A.
N.A.
N.A.
57.4
P-Site Identity:
100
0
100
100
N.A.
86.6
86.6
N.A.
13.3
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
0
100
100
N.A.
86.6
86.6
N.A.
26.6
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.6
30.4
36.7
Protein Similarity:
N.A.
N.A.
N.A.
55.8
49.5
55.9
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
40
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
42
9
0
0
0
0
0
0
9
% A
% Cys:
0
17
9
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
50
17
0
0
42
9
0
9
9
9
0
0
9
17
0
% D
% Glu:
17
9
0
9
0
0
9
9
9
9
42
17
50
0
0
% E
% Phe:
0
0
42
17
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
9
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
17
0
9
0
9
0
0
0
9
0
9
% H
% Ile:
9
0
0
0
0
9
0
0
9
0
0
9
0
0
9
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
9
% K
% Leu:
0
17
9
17
0
0
0
17
0
34
9
50
25
9
0
% L
% Met:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
9
9
0
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
42
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
9
0
42
0
9
9
0
9
42
% R
% Ser:
9
25
9
9
0
59
9
42
9
34
9
9
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
9
0
0
42
9
% T
% Val:
0
0
9
0
9
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _