KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH3
All Species:
9.09
Human Site:
S173
Identified Species:
18.18
UniProt:
P20585
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20585
NP_002430.2
1137
127440
S173
C
T
D
F
D
D
I
S
L
L
H
A
K
N
A
Chimpanzee
Pan troglodytes
XP_526872
653
74467
Rhesus Macaque
Macaca mulatta
XP_001110439
1124
126700
S161
C
T
D
F
D
D
I
S
L
L
R
A
K
N
A
Dog
Lupus familis
XP_536307
1124
126796
T161
C
T
D
F
D
D
I
T
H
L
R
A
K
N
V
Cat
Felis silvestris
Mouse
Mus musculus
P13705
1091
123056
T133
L
E
V
L
P
R
C
T
D
F
E
D
I
T
L
Rat
Rattus norvegicus
XP_001065837
1105
124697
T133
L
A
V
L
P
K
C
T
D
F
E
D
I
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512218
1058
119728
S142
I
C
E
N
L
Q
N
S
S
D
L
K
L
T
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103184
1083
121769
Q134
K
A
E
I
S
A
S
Q
Q
H
N
V
I
M
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193092
988
109454
A94
A
S
S
S
S
C
L
A
G
E
T
K
D
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65607
1081
119348
F134
V
G
Y
R
Y
R
F
F
G
E
D
A
E
I
A
Baker's Yeast
Sacchar. cerevisiae
P25336
1018
116515
K123
E
E
D
F
V
K
K
K
A
R
K
S
P
T
A
Red Bread Mold
Neurospora crassa
Q7SD11
1145
125674
Q148
D
S
M
F
S
Y
R
Q
R
D
T
E
S
A
A
Conservation
Percent
Protein Identity:
100
54.1
95.6
83.1
N.A.
78.3
78.8
N.A.
71.5
N.A.
N.A.
50.4
N.A.
N.A.
N.A.
N.A.
40.8
Protein Similarity:
100
56.1
96.6
88.7
N.A.
86
86.2
N.A.
81.2
N.A.
N.A.
68.5
N.A.
N.A.
N.A.
N.A.
57.4
P-Site Identity:
100
0
93.3
73.3
N.A.
0
0
N.A.
6.6
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
0
93.3
80
N.A.
6.6
6.6
N.A.
13.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.6
30.4
36.7
Protein Similarity:
N.A.
N.A.
N.A.
55.8
49.5
55.9
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
0
0
0
9
0
9
9
0
0
34
0
9
42
% A
% Cys:
25
9
0
0
0
9
17
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
34
0
25
25
0
0
17
17
9
17
9
0
0
% D
% Glu:
9
17
17
0
0
0
0
0
0
17
17
9
9
0
0
% E
% Phe:
0
0
0
42
0
0
9
9
0
17
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
17
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
9
9
0
0
0
9
% H
% Ile:
9
0
0
9
0
0
25
0
0
0
0
0
25
9
0
% I
% Lys:
9
0
0
0
0
17
9
9
0
0
9
17
25
0
0
% K
% Leu:
17
0
0
17
9
0
9
0
17
25
9
0
9
0
17
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
9
0
0
9
0
0
0
9
0
0
25
9
% N
% Pro:
0
0
0
0
17
0
0
0
0
0
0
0
9
9
0
% P
% Gln:
0
0
0
0
0
9
0
17
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
17
9
0
9
9
17
0
0
0
9
% R
% Ser:
0
17
9
9
25
0
9
25
9
0
0
9
9
0
0
% S
% Thr:
0
25
0
0
0
0
0
25
0
0
17
0
0
34
0
% T
% Val:
9
0
17
0
9
0
0
0
0
0
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
9
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _