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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAB5A All Species: 26.36
Human Site: T202 Identified Species: 44.62
UniProt: P20339 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20339 NP_004153.2 215 23659 T202 R G R G V D L T E P T Q P T R
Chimpanzee Pan troglodytes XP_516319 216 23697 T203 G R G G V D L T E P T Q P T R
Rhesus Macaque Macaca mulatta XP_001086669 215 23622 T202 R G R G V D L T E P T R P T R
Dog Lupus familis XP_856128 222 24457 H209 R S R G V D L H E Q S Q Q N K
Cat Felis silvestris
Mouse Mus musculus Q9CQD1 215 23580 T202 R G R G V D L T E P A Q P A R
Rat Rattus norvegicus Q6GQP4 194 21350 L182 G N S G G I K L G N Q S L Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508982 215 23635 T202 R G R G V D L T E H T L P S R
Chicken Gallus gallus Q98932 216 23535 Q203 R N R V V D L Q E S S Q P S R
Frog Xenopus laevis NP_001080535 216 23558 T203 R G R G V D L T E T A Q P T K
Zebra Danio Brachydanio rerio NP_958893 216 23476 T203 R S R G V D L T E T A Q P T K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783878 216 23603 T203 T N R G V D L T E S N Q Q S S
Poplar Tree Populus trichocarpa
Maize Zea mays Q05737 203 22457 G191 P A T V Q I R G Q P V N Q K T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P31582 200 21635 G188 T G M V L P N G P G A T A V S
Baker's Yeast Sacchar. cerevisiae P36017 210 23062 A197 N Q R V D L N A A N D G T S A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 94.4 79.2 N.A. 98.1 45.1 N.A. 97.2 87 91.6 92.5 N.A. N.A. N.A. N.A. 81.4
Protein Similarity: 100 99.5 98.5 88.2 N.A. 99 62.7 N.A. 99 91.6 95.3 94.9 N.A. N.A. N.A. N.A. 88.4
P-Site Identity: 100 80 93.3 53.3 N.A. 86.6 6.6 N.A. 80 60 80 73.3 N.A. N.A. N.A. N.A. 53.3
P-Site Similarity: 100 80 100 66.6 N.A. 86.6 6.6 N.A. 86.6 73.3 86.6 80 N.A. N.A. N.A. N.A. 60
Percent
Protein Identity: N.A. 40.4 N.A. 59 54.4 N.A.
Protein Similarity: N.A. 57.2 N.A. 70.7 68.3 N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. 13.3 N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 8 8 0 29 0 8 8 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 72 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 72 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 15 43 8 72 8 0 0 15 8 8 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 22 % K
% Leu: 0 0 0 0 8 8 72 8 0 0 0 8 8 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 22 0 0 0 0 15 0 0 15 8 8 0 8 0 % N
% Pro: 8 0 0 0 0 8 0 0 8 36 0 0 58 0 0 % P
% Gln: 0 8 0 0 8 0 0 8 8 8 8 58 22 8 0 % Q
% Arg: 58 8 72 0 0 0 8 0 0 0 0 8 0 0 43 % R
% Ser: 0 15 8 0 0 0 0 0 0 15 15 8 0 29 15 % S
% Thr: 15 0 8 0 0 0 0 58 0 15 29 8 8 36 8 % T
% Val: 0 0 0 29 72 0 0 0 0 0 8 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _