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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB5A
All Species:
42.42
Human Site:
S123
Identified Species:
71.79
UniProt:
P20339
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20339
NP_004153.2
215
23659
S123
K
E
L
Q
R
Q
A
S
P
N
I
V
I
A
L
Chimpanzee
Pan troglodytes
XP_516319
216
23697
S123
K
E
L
Q
R
Q
A
S
P
N
I
V
I
A
L
Rhesus Macaque
Macaca mulatta
XP_001086669
215
23622
S123
K
E
L
Q
R
Q
A
S
P
N
T
V
I
A
L
Dog
Lupus familis
XP_856128
222
24457
S123
K
E
L
Q
R
Q
A
S
P
S
I
V
I
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQD1
215
23580
S123
K
E
L
Q
R
Q
A
S
P
N
I
V
I
A
L
Rat
Rattus norvegicus
Q6GQP4
194
21350
N118
I
V
M
A
I
A
G
N
K
C
D
L
S
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508982
215
23635
S123
K
E
L
Q
R
Q
A
S
P
N
I
V
I
A
L
Chicken
Gallus gallus
Q98932
216
23535
S124
K
E
L
Q
R
Q
A
S
P
N
I
V
I
A
L
Frog
Xenopus laevis
NP_001080535
216
23558
S124
K
E
L
Q
R
Q
A
S
P
N
I
V
I
A
L
Zebra Danio
Brachydanio rerio
NP_958893
216
23476
S124
K
E
L
Q
R
Q
A
S
P
N
I
V
I
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783878
216
23603
S122
K
E
L
Q
R
Q
A
S
P
N
I
V
I
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q05737
203
22457
T126
V
G
N
K
S
D
L
T
A
N
K
V
V
A
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P31582
200
21635
N123
M
V
M
A
L
A
G
N
K
A
D
L
L
D
A
Baker's Yeast
Sacchar. cerevisiae
P36017
210
23062
G129
I
D
M
L
Q
E
G
G
E
R
K
V
A
R
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
94.4
79.2
N.A.
98.1
45.1
N.A.
97.2
87
91.6
92.5
N.A.
N.A.
N.A.
N.A.
81.4
Protein Similarity:
100
99.5
98.5
88.2
N.A.
99
62.7
N.A.
99
91.6
95.3
94.9
N.A.
N.A.
N.A.
N.A.
88.4
P-Site Identity:
100
100
93.3
93.3
N.A.
100
0
N.A.
100
100
100
100
N.A.
N.A.
N.A.
N.A.
100
P-Site Similarity:
100
100
93.3
100
N.A.
100
26.6
N.A.
100
100
100
100
N.A.
N.A.
N.A.
N.A.
100
Percent
Protein Identity:
N.A.
40.4
N.A.
59
54.4
N.A.
Protein Similarity:
N.A.
57.2
N.A.
70.7
68.3
N.A.
P-Site Identity:
N.A.
20
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
40
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
0
15
72
0
8
8
0
0
8
79
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
8
0
0
0
0
15
0
0
15
0
% D
% Glu:
0
72
0
0
0
8
0
0
8
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
22
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
0
0
0
8
0
0
0
0
0
65
0
72
0
8
% I
% Lys:
72
0
0
8
0
0
0
0
15
0
15
0
0
0
0
% K
% Leu:
0
0
72
8
8
0
8
0
0
0
0
15
8
0
72
% L
% Met:
8
0
22
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
15
0
72
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
72
0
0
0
0
0
0
% P
% Gln:
0
0
0
72
8
72
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
72
0
0
0
0
8
0
0
0
8
0
% R
% Ser:
0
0
0
0
8
0
0
72
0
8
0
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% T
% Val:
8
15
0
0
0
0
0
0
0
0
0
86
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _