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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD22
All Species:
14.24
Human Site:
Y822
Identified Species:
39.17
UniProt:
P20273
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20273
NP_001762.2
847
95348
Y822
P
E
D
E
G
I
H
Y
S
E
L
I
Q
F
G
Chimpanzee
Pan troglodytes
Q9N1E6
332
37710
S312
G
K
Y
C
C
Q
V
S
N
D
V
G
P
G
R
Rhesus Macaque
Macaca mulatta
XP_001111493
848
95478
Y823
P
E
D
E
G
I
H
Y
S
E
L
I
Q
F
G
Dog
Lupus familis
XP_533695
853
96035
I826
E
N
V
E
D
E
G
I
H
Y
S
E
L
V
H
Cat
Felis silvestris
Mouse
Mus musculus
P35329
862
96564
Y837
P
E
D
E
S
I
H
Y
S
E
L
V
Q
F
G
Rat
Rattus norvegicus
NP_001100973
852
95445
Y827
P
E
D
E
S
I
H
Y
S
E
L
V
Q
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q0WYX8
949
106007
I885
P
P
G
P
F
Q
I
I
F
E
G
V
R
G
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001091715
1043
117185
N1020
A
V
K
E
V
K
P
N
Q
K
R
H
F
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796903
1010
110769
W931
P
P
S
Y
A
P
S
W
D
S
Y
E
N
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.3
86.5
64.4
N.A.
60
59
N.A.
N.A.
20
N.A.
24.7
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
100
38.4
91.7
76.7
N.A.
73.4
74
N.A.
N.A.
37.9
N.A.
42.5
N.A.
N.A.
N.A.
N.A.
36
P-Site Identity:
100
0
100
6.6
N.A.
86.6
86.6
N.A.
N.A.
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
100
6.6
N.A.
93.3
93.3
N.A.
N.A.
26.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
12
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
45
0
12
0
0
0
12
12
0
0
0
0
0
% D
% Glu:
12
45
0
67
0
12
0
0
0
56
0
23
0
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
12
0
0
0
12
45
0
% F
% Gly:
12
0
12
0
23
0
12
0
0
0
12
12
0
23
45
% G
% His:
0
0
0
0
0
0
45
0
12
0
0
12
0
0
12
% H
% Ile:
0
0
0
0
0
45
12
23
0
0
0
23
0
0
0
% I
% Lys:
0
12
12
0
0
12
0
0
0
12
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
45
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
12
12
0
0
0
12
0
0
% N
% Pro:
67
23
0
12
0
12
12
0
0
0
0
0
12
12
12
% P
% Gln:
0
0
0
0
0
23
0
0
12
0
0
0
45
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
12
0
12
0
12
% R
% Ser:
0
0
12
0
23
0
12
12
45
12
12
0
0
12
12
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% T
% Val:
0
12
12
0
12
0
12
0
0
0
12
34
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
12
0
0
0
45
0
12
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _