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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK2A2 All Species: 48.48
Human Site: Y324 Identified Species: 62.75
UniProt: P19784 Number Species: 17
    Phosphosite Substitution
    Charge Score: 0.24
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19784 NP_001887.1 350 41213 Y324 K E A M E H P Y F Y P V V K E
Chimpanzee Pan troglodytes XP_511002 323 38151 Y297 K E A M E H P Y F Y P V V K E
Rhesus Macaque Macaca mulatta XP_001101458 590 66136 Y564 K E A M E H P Y F Y P V V K E
Dog Lupus familis XP_535282 336 39497 Y310 K E A M E H P Y F Y P V V K E
Cat Felis silvestris
Mouse Mus musculus O54833 350 41197 Y324 K E A M E H P Y F Y P V V K E
Rat Rattus norvegicus P19139 391 45055 Y323 R E A M E H P Y F Y T V V K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507666 350 41142 Y324 K E A M E H P Y F Y P V V K E
Chicken Gallus gallus P21869 350 41228 Y324 K E A M E H P Y F Y P V V K E
Frog Xenopus laevis P28020 392 45169 Y323 R E A M D H P Y F Y P I V K D
Zebra Danio Brachydanio rerio A8WIP6 344 39006 H318 R Q R M Q P P H E F T V D R P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08181 336 39941 D309 L L R Y D H V D R L T A R E A
Honey Bee Apis mellifera XP_393260 350 41645 Y321 R E A M E H P Y F Y P I V K D
Nematode Worm Caenorhab. elegans P18334 360 42239 Y322 Q E A M G H E Y F R P V V E A
Sea Urchin Strong. purpuratus XP_785475 398 46271 Y321 R E A M E H P Y F Y P V V K E
Poplar Tree Populus trichocarpa
Maize Zea mays P28523 332 39212 E306 L L R Y D H Q E R L T A L E A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q08466 333 39346 D303 L D K L L R Y D H Q D R L T A
Baker's Yeast Sacchar. cerevisiae P19454 339 39385 E306 E T K L A V P E V V D L I D N
Red Bread Mold Neurospora crassa Q8TG13 336 39621 H302 D K L L R Y D H N E R L T A K
Conservation
Percent
Protein Identity: 100 91.7 57.9 91.4 N.A. 98.8 75.1 N.A. 98.2 97.1 75 23.7 N.A. 77.4 79.4 75 71.3
Protein Similarity: 100 92 58.9 92.8 N.A. 99.7 82 N.A. 99.4 98.5 82.1 47.1 N.A. 86 89.1 86.1 79.4
P-Site Identity: 100 100 100 100 N.A. 100 80 N.A. 100 100 73.3 20 N.A. 6.6 80 60 93.3
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 100 100 100 60 N.A. 20 100 73.3 100
Percent
Protein Identity: N.A. 69.7 N.A. 67.4 56 65.4
Protein Similarity: N.A. 82.2 N.A. 81.4 70.2 79.7
P-Site Identity: N.A. 6.6 N.A. 0 6.6 0
P-Site Similarity: N.A. 26.6 N.A. 20 33.3 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 67 0 6 0 0 0 0 0 0 12 0 6 23 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 6 0 0 17 0 6 12 0 0 12 0 6 6 17 % D
% Glu: 6 67 0 0 56 0 6 12 6 6 0 0 0 17 45 % E
% Phe: 0 0 0 0 0 0 0 0 67 6 0 0 0 0 0 % F
% Gly: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 78 0 12 6 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 12 6 0 0 % I
% Lys: 39 6 12 0 0 0 0 0 0 0 0 0 0 62 6 % K
% Leu: 17 12 6 17 6 0 0 0 0 12 0 12 12 0 0 % L
% Met: 0 0 0 73 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 6 % N
% Pro: 0 0 0 0 0 6 73 0 0 0 62 0 0 0 6 % P
% Gln: 6 6 0 0 6 0 6 0 0 6 0 0 0 0 0 % Q
% Arg: 28 0 17 0 6 6 0 0 12 6 6 6 6 6 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 6 0 0 0 0 0 0 0 0 23 0 6 6 0 % T
% Val: 0 0 0 0 0 6 6 0 6 6 0 62 67 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 0 6 6 67 0 62 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _