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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK2A2 All Species: 16.36
Human Site: Y27 Identified Species: 21.18
UniProt: P19784 Number Species: 17
    Phosphosite Substitution
    Charge Score: 0.53
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19784 NP_001887.1 350 41213 Y27 R S R E Y W D Y E A H V P S W
Chimpanzee Pan troglodytes XP_511002 323 38151 F28 R G K Y S E V F E A I N I T N
Rhesus Macaque Macaca mulatta XP_001101458 590 66136 V267 C F F T R G E V W G P G I D A
Dog Lupus familis XP_535282 336 39497 L28 S N Q D D Y Q L V R K L G R G
Cat Felis silvestris
Mouse Mus musculus O54833 350 41197 Y27 R S R E Y W D Y E A H V P S W
Rat Rattus norvegicus P19139 391 45055 D37 V V E W G N Q D D Y Q L V R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507666 350 41142 Y27 R S R D Y W D Y E A H V P S W
Chicken Gallus gallus P21869 350 41228 Y27 R S R E Y W D Y E A H V P S W
Frog Xenopus laevis P28020 392 45169 D37 V V E W G N Q D D Y Q L V R K
Zebra Danio Brachydanio rerio A8WIP6 344 39006 T29 K H I E T G E T V A L K K V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08181 336 39941 Y27 E Y W D Y E N Y V V D W G N Q
Honey Bee Apis mellifera XP_393260 350 41645 D35 V V D W G Q Q D D Y Q L V R K
Nematode Worm Caenorhab. elegans P18334 360 42239 D36 M I E W G Q I D D Y Q L V R K
Sea Urchin Strong. purpuratus XP_785475 398 46271 D35 V V E W G Q Q D D Y Q I V R K
Poplar Tree Populus trichocarpa
Maize Zea mays P28523 332 39212 D32 T V Q W G E Q D D Y E V V R K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q08466 333 39346 D32 N V Q W G E Q D D Y E V V R K
Baker's Yeast Sacchar. cerevisiae P19454 339 39385 E37 P Q E Y W D Y E Q G V T I D W
Red Bread Mold Neurospora crassa Q8TG13 336 39621 E30 N I S W G V L E N Y E V V R K
Conservation
Percent
Protein Identity: 100 91.7 57.9 91.4 N.A. 98.8 75.1 N.A. 98.2 97.1 75 23.7 N.A. 77.4 79.4 75 71.3
Protein Similarity: 100 92 58.9 92.8 N.A. 99.7 82 N.A. 99.4 98.5 82.1 47.1 N.A. 86 89.1 86.1 79.4
P-Site Identity: 100 20 0 0 N.A. 100 0 N.A. 93.3 100 0 13.3 N.A. 13.3 0 0 0
P-Site Similarity: 100 40 6.6 33.3 N.A. 100 13.3 N.A. 100 100 13.3 26.6 N.A. 33.3 13.3 13.3 13.3
Percent
Protein Identity: N.A. 69.7 N.A. 67.4 56 65.4
Protein Similarity: N.A. 82.2 N.A. 81.4 70.2 79.7
P-Site Identity: N.A. 6.6 N.A. 6.6 6.6 6.6
P-Site Similarity: N.A. 20 N.A. 20 20 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 34 0 0 0 0 12 % A
% Cys: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 6 17 6 6 23 39 39 0 6 0 0 12 0 % D
% Glu: 6 0 28 23 0 23 12 12 28 0 17 0 0 0 0 % E
% Phe: 0 6 6 0 0 0 0 6 0 0 0 0 0 0 0 % F
% Gly: 0 6 0 0 45 12 0 0 0 12 0 6 12 0 6 % G
% His: 0 6 0 0 0 0 0 0 0 0 23 0 0 0 0 % H
% Ile: 0 12 6 0 0 0 6 0 0 0 6 6 17 0 0 % I
% Lys: 6 0 6 0 0 0 0 0 0 0 6 6 6 0 45 % K
% Leu: 0 0 0 0 0 0 6 6 0 0 6 28 0 0 0 % L
% Met: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 6 0 0 0 12 6 0 6 0 0 6 0 6 6 % N
% Pro: 6 0 0 0 0 0 0 0 0 0 6 0 23 0 0 % P
% Gln: 0 6 17 0 0 17 39 0 6 0 28 0 0 0 6 % Q
% Arg: 28 0 23 0 6 0 0 0 0 6 0 0 0 50 0 % R
% Ser: 6 23 6 0 6 0 0 0 0 0 0 0 0 23 0 % S
% Thr: 6 0 0 6 6 0 0 6 0 0 0 6 0 6 0 % T
% Val: 23 34 0 0 0 6 6 6 17 6 6 39 45 6 0 % V
% Trp: 0 0 6 45 6 23 0 0 6 0 0 6 0 0 28 % W
% Tyr: 0 6 0 12 28 6 6 28 0 45 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _