Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK2A2 All Species: 63.33
Human Site: T109 Identified Species: 81.96
UniProt: P19784 Number Species: 17
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19784 NP_001887.1 350 41213 T109 V K D P V S K T P A L V F E Y
Chimpanzee Pan troglodytes XP_511002 323 38151 D94 F E Y I N N T D F K Q L Y Q I
Rhesus Macaque Macaca mulatta XP_001101458 590 66136 T349 V K D P V S K T P A L V F E Y
Dog Lupus familis XP_535282 336 39497 T95 V K D P V S K T P A L V F E Y
Cat Felis silvestris
Mouse Mus musculus O54833 350 41197 T109 V K D P V S K T P A L V F E Y
Rat Rattus norvegicus P19139 391 45055 T108 V K D P V S R T P A L V F E H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507666 350 41142 T109 V K D P V S K T P A L V F E Y
Chicken Gallus gallus P21869 350 41228 T109 V K D P V S K T P A L V F E Y
Frog Xenopus laevis P28020 392 45169 T108 V K D P V S R T P A L V F E H
Zebra Danio Brachydanio rerio A8WIP6 344 39006 S95 L S E V I R N S Q R P L T A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08181 336 39941 T106 V K D P V S R T P A L I F E H
Honey Bee Apis mellifera XP_393260 350 41645 T106 V K D P V S R T P A L I F E H
Nematode Worm Caenorhab. elegans P18334 360 42239 T107 V K D P I S R T P A L I F E H
Sea Urchin Strong. purpuratus XP_785475 398 46271 T106 V K D P V S R T P A L I F E Y
Poplar Tree Populus trichocarpa
Maize Zea mays P28523 332 39212 T103 V R D Q H S K T P S L I F E Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q08466 333 39346 T103 V R D Q H S K T P S L I F E Y
Baker's Yeast Sacchar. cerevisiae P19454 339 39385 G107 T G G P N V V G L Y D I V Q D
Red Bread Mold Neurospora crassa Q8TG13 336 39621 T101 V R D S Q S K T P S L I F E Y
Conservation
Percent
Protein Identity: 100 91.7 57.9 91.4 N.A. 98.8 75.1 N.A. 98.2 97.1 75 23.7 N.A. 77.4 79.4 75 71.3
Protein Similarity: 100 92 58.9 92.8 N.A. 99.7 82 N.A. 99.4 98.5 82.1 47.1 N.A. 86 89.1 86.1 79.4
P-Site Identity: 100 0 100 100 N.A. 100 86.6 N.A. 100 100 86.6 0 N.A. 80 80 73.3 86.6
P-Site Similarity: 100 33.3 100 100 N.A. 100 100 N.A. 100 100 100 33.3 N.A. 100 100 100 100
Percent
Protein Identity: N.A. 69.7 N.A. 67.4 56 65.4
Protein Similarity: N.A. 82.2 N.A. 81.4 70.2 79.7
P-Site Identity: N.A. 66.6 N.A. 66.6 6.6 66.6
P-Site Similarity: N.A. 86.6 N.A. 86.6 20 86.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 67 0 0 0 6 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 84 0 0 0 0 6 0 0 6 0 0 0 6 % D
% Glu: 0 6 6 0 0 0 0 0 0 0 0 0 0 84 0 % E
% Phe: 6 0 0 0 0 0 0 0 6 0 0 0 84 0 0 % F
% Gly: 0 6 6 0 0 0 0 6 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 28 % H
% Ile: 0 0 0 6 12 0 0 0 0 0 0 45 0 0 6 % I
% Lys: 0 67 0 0 0 0 50 0 0 6 0 0 0 0 0 % K
% Leu: 6 0 0 0 0 0 0 0 6 0 84 12 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 12 6 6 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 73 0 0 0 0 84 0 6 0 0 0 0 % P
% Gln: 0 0 0 12 6 0 0 0 6 0 6 0 0 12 0 % Q
% Arg: 0 17 0 0 0 6 34 0 0 6 0 0 0 0 0 % R
% Ser: 0 6 0 6 0 84 0 6 0 17 0 0 0 0 6 % S
% Thr: 6 0 0 0 0 0 6 84 0 0 0 0 6 0 0 % T
% Val: 84 0 0 6 62 6 6 0 0 0 0 45 6 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 0 0 0 0 0 0 6 0 0 6 0 56 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _