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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK2A2 All Species: 22.12
Human Site: S52 Identified Species: 28.63
UniProt: P19784 Number Species: 17
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19784 NP_001887.1 350 41213 S52 K L G R G K Y S E V F E A I N
Chimpanzee Pan troglodytes XP_511002 323 38151 K53 P V K K K K I K R E V K I L E
Rhesus Macaque Macaca mulatta XP_001101458 590 66136 S292 K L G R G K Y S E V F E A I N
Dog Lupus familis XP_535282 336 39497 V53 I T N N E R V V V K I L K P V
Cat Felis silvestris
Mouse Mus musculus O54833 350 41197 S52 K L G R G K Y S E V F E A I N
Rat Rattus norvegicus P19139 391 45055 N62 E A I N I T N N E K V V V K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507666 350 41142 S52 K L G R G K Y S E V F E A I N
Chicken Gallus gallus P21869 350 41228 S52 K L G R G K Y S E V F E A I N
Frog Xenopus laevis P28020 392 45169 N62 E A I N I T N N E K V V V K I
Zebra Danio Brachydanio rerio A8WIP6 344 39006 A54 Q A L R E I K A L Q E I E D N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08181 336 39941 F52 R G K Y S E V F E A I N I T T
Honey Bee Apis mellifera XP_393260 350 41645 N60 E A I N I T N N E K C V V K I
Nematode Worm Caenorhab. elegans P18334 360 42239 D61 E G F K M S T D E K V V V K I
Sea Urchin Strong. purpuratus XP_785475 398 46271 N60 E A V N I T S N E K C V I K I
Poplar Tree Populus trichocarpa
Maize Zea mays P28523 332 39212 N57 E G I N V N N N E K C I I K I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q08466 333 39346 N57 E G I N M N N N E K C I I K I
Baker's Yeast Sacchar. cerevisiae P19454 339 39385 S62 K I G R G K Y S E V F S G R C
Red Bread Mold Neurospora crassa Q8TG13 336 39621 Y55 E G I N V V N Y Q K C V I K V
Conservation
Percent
Protein Identity: 100 91.7 57.9 91.4 N.A. 98.8 75.1 N.A. 98.2 97.1 75 23.7 N.A. 77.4 79.4 75 71.3
Protein Similarity: 100 92 58.9 92.8 N.A. 99.7 82 N.A. 99.4 98.5 82.1 47.1 N.A. 86 89.1 86.1 79.4
P-Site Identity: 100 6.6 100 0 N.A. 100 6.6 N.A. 100 100 6.6 13.3 N.A. 6.6 6.6 6.6 6.6
P-Site Similarity: 100 33.3 100 6.6 N.A. 100 20 N.A. 100 100 20 26.6 N.A. 20 20 20 20
Percent
Protein Identity: N.A. 69.7 N.A. 67.4 56 65.4
Protein Similarity: N.A. 82.2 N.A. 81.4 70.2 79.7
P-Site Identity: N.A. 6.6 N.A. 6.6 66.6 0
P-Site Similarity: N.A. 20 N.A. 20 73.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 28 0 0 0 0 0 6 0 6 0 0 28 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 28 0 0 0 6 % C
% Asp: 0 0 0 0 0 0 0 6 0 0 0 0 0 6 0 % D
% Glu: 45 0 0 0 12 6 0 0 78 6 6 28 6 0 6 % E
% Phe: 0 0 6 0 0 0 0 6 0 0 34 0 0 0 0 % F
% Gly: 0 28 34 0 34 0 0 0 0 0 0 0 6 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 6 6 34 0 23 6 6 0 0 0 12 17 34 28 39 % I
% Lys: 34 0 12 12 6 39 6 6 0 50 0 6 6 45 0 % K
% Leu: 0 28 6 0 0 0 0 0 6 0 0 6 0 6 0 % L
% Met: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 6 45 0 12 34 34 0 0 0 6 0 0 34 % N
% Pro: 6 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % P
% Gln: 6 0 0 0 0 0 0 0 6 6 0 0 0 0 0 % Q
% Arg: 6 0 0 39 0 6 0 0 6 0 0 0 0 6 0 % R
% Ser: 0 0 0 0 6 6 6 34 0 0 0 6 0 0 0 % S
% Thr: 0 6 0 0 0 23 6 0 0 0 0 0 0 6 6 % T
% Val: 0 6 6 0 12 6 12 6 6 34 23 34 23 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 6 0 0 34 6 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _