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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK2A2 All Species: 47.88
Human Site: S295 Identified Species: 61.96
UniProt: P19784 Number Species: 17
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19784 NP_001887.1 350 41213 S295 S E N R H L V S P E A L D L L
Chimpanzee Pan troglodytes XP_511002 323 38151 S268 S E N R H L V S P E A L D L L
Rhesus Macaque Macaca mulatta XP_001101458 590 66136 S535 S E N R H L V S P E A L D L L
Dog Lupus familis XP_535282 336 39497 S281 S E N R H L V S P E A L D L L
Cat Felis silvestris
Mouse Mus musculus O54833 350 41197 S295 S E N R H L V S P E A L D L L
Rat Rattus norvegicus P19139 391 45055 S294 S E N Q H L V S P E A L D F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507666 350 41142 S295 S E N R H L V S P E A L D L L
Chicken Gallus gallus P21869 350 41228 S295 S E N R H L V S P E V L D L L
Frog Xenopus laevis P28020 392 45169 S294 S E N Q H L V S P E A L D F L
Zebra Danio Brachydanio rerio A8WIP6 344 39006 F289 A L L H P Y F F T D P L P A H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08181 336 39941 E280 R H S R K R W E R F V H S D N
Honey Bee Apis mellifera XP_393260 350 41645 S292 S E N Q H L V S H E S L D F L
Nematode Worm Caenorhab. elegans P18334 360 42239 T293 A E N Q H L V T P E A L D F L
Sea Urchin Strong. purpuratus XP_785475 398 46271 S292 S E N Q H L V S P E A L D F L
Poplar Tree Populus trichocarpa
Maize Zea mays P28523 332 39212 L277 R H S R K P W L K F M N A D N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q08466 333 39346 K274 L V G R H S R K P W S K F I N
Baker's Yeast Sacchar. cerevisiae P19454 339 39385 P277 G K Y G L H L P S E Y D N I M
Red Bread Mold Neurospora crassa Q8TG13 336 39621 P273 L G R F Q R K P W H S F I N A
Conservation
Percent
Protein Identity: 100 91.7 57.9 91.4 N.A. 98.8 75.1 N.A. 98.2 97.1 75 23.7 N.A. 77.4 79.4 75 71.3
Protein Similarity: 100 92 58.9 92.8 N.A. 99.7 82 N.A. 99.4 98.5 82.1 47.1 N.A. 86 89.1 86.1 79.4
P-Site Identity: 100 100 100 100 N.A. 100 86.6 N.A. 100 93.3 86.6 6.6 N.A. 6.6 73.3 73.3 86.6
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 100 93.3 93.3 20 N.A. 13.3 86.6 93.3 93.3
Percent
Protein Identity: N.A. 69.7 N.A. 67.4 56 65.4
Protein Similarity: N.A. 82.2 N.A. 81.4 70.2 79.7
P-Site Identity: N.A. 6.6 N.A. 20 6.6 0
P-Site Similarity: N.A. 13.3 N.A. 33.3 40 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 0 0 0 0 0 0 56 0 6 6 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 6 0 6 67 12 0 % D
% Glu: 0 67 0 0 0 0 0 6 0 73 0 0 0 0 0 % E
% Phe: 0 0 0 6 0 0 6 6 0 12 0 6 6 28 0 % F
% Gly: 6 6 6 6 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 12 0 6 73 6 0 0 6 6 0 6 0 0 6 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 6 12 0 % I
% Lys: 0 6 0 0 12 0 6 6 6 0 0 6 0 0 0 % K
% Leu: 12 6 6 0 6 67 6 6 0 0 0 73 0 39 67 % L
% Met: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 6 % M
% Asn: 0 0 67 0 0 0 0 0 0 0 0 6 6 6 17 % N
% Pro: 0 0 0 0 6 6 0 12 67 0 6 0 6 0 0 % P
% Gln: 0 0 0 28 6 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 12 0 6 56 0 12 6 0 6 0 0 0 0 0 0 % R
% Ser: 62 0 12 0 0 6 0 62 6 0 17 0 6 0 0 % S
% Thr: 0 0 0 0 0 0 0 6 6 0 0 0 0 0 0 % T
% Val: 0 6 0 0 0 0 67 0 0 0 12 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 12 0 6 6 0 0 0 0 0 % W
% Tyr: 0 0 6 0 0 6 0 0 0 0 6 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _