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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK2A2 All Species: 14.85
Human Site: S21 Identified Species: 19.22
UniProt: P19784 Number Species: 17
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19784 NP_001887.1 350 41213 S21 A E V N S L R S R E Y W D Y E
Chimpanzee Pan troglodytes XP_511002 323 38151 G22 L V R K L G R G K Y S E V F E
Rhesus Macaque Macaca mulatta XP_001101458 590 66136 F261 P L S P K E C F F T R G E V W
Dog Lupus familis XP_535282 336 39497 N22 V T L A F H S N Q D D Y Q L V
Cat Felis silvestris
Mouse Mus musculus O54833 350 41197 S21 A E V N S L R S R E Y W D Y E
Rat Rattus norvegicus P19139 391 45055 V31 W D Y E S H V V E W G N Q D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507666 350 41142 S21 A E V N S L R S R D Y W D Y E
Chicken Gallus gallus P21869 350 41228 S21 A E V N S L R S R E Y W D Y E
Frog Xenopus laevis P28020 392 45169 V31 W D Y E S H V V E W G N Q D D
Zebra Danio Brachydanio rerio A8WIP6 344 39006 H23 G I V F K A K H I E T G E T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08181 336 39941 Y21 N A H K P D E Y W D Y E N Y V
Honey Bee Apis mellifera XP_393260 350 41645 V29 W D Y E S Y V V D W G Q Q D D
Nematode Worm Caenorhab. elegans P18334 360 42239 I30 W D Y E A H M I E W G Q I D D
Sea Urchin Strong. purpuratus XP_785475 398 46271 V29 W D Y E S H V V E W G Q Q D D
Poplar Tree Populus trichocarpa
Maize Zea mays P28523 332 39212 V26 W D Y E A L T V Q W G E Q D D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q08466 333 39346 V26 W D Y E S L N V Q W G E Q D D
Baker's Yeast Sacchar. cerevisiae P19454 339 39385 Q31 N A C E E R P Q E Y W D Y E Q
Red Bread Mold Neurospora crassa Q8TG13 336 39621 I24 W D Y D S V N I S W G V L E N
Conservation
Percent
Protein Identity: 100 91.7 57.9 91.4 N.A. 98.8 75.1 N.A. 98.2 97.1 75 23.7 N.A. 77.4 79.4 75 71.3
Protein Similarity: 100 92 58.9 92.8 N.A. 99.7 82 N.A. 99.4 98.5 82.1 47.1 N.A. 86 89.1 86.1 79.4
P-Site Identity: 100 13.3 0 0 N.A. 100 6.6 N.A. 93.3 100 6.6 13.3 N.A. 13.3 6.6 0 6.6
P-Site Similarity: 100 26.6 6.6 33.3 N.A. 100 20 N.A. 100 100 20 26.6 N.A. 26.6 20 20 20
Percent
Protein Identity: N.A. 69.7 N.A. 67.4 56 65.4
Protein Similarity: N.A. 82.2 N.A. 81.4 70.2 79.7
P-Site Identity: N.A. 6.6 N.A. 13.3 0 6.6
P-Site Similarity: N.A. 33.3 N.A. 33.3 13.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 23 12 0 6 12 6 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 6 0 0 0 6 0 0 0 0 0 0 0 0 % C
% Asp: 0 45 0 6 0 6 0 0 6 17 6 6 23 39 39 % D
% Glu: 0 23 0 45 6 6 6 0 28 23 0 23 12 12 28 % E
% Phe: 0 0 0 6 6 0 0 6 6 0 0 0 0 6 0 % F
% Gly: 6 0 0 0 0 6 0 6 0 0 45 12 0 0 0 % G
% His: 0 0 6 0 0 28 0 6 0 0 0 0 0 0 0 % H
% Ile: 0 6 0 0 0 0 0 12 6 0 0 0 6 0 0 % I
% Lys: 0 0 0 12 12 0 6 0 6 0 0 0 0 0 0 % K
% Leu: 6 6 6 0 6 34 0 0 0 0 0 0 6 6 0 % L
% Met: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 0 23 0 0 12 6 0 0 0 12 6 0 6 % N
% Pro: 6 0 0 6 6 0 6 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 6 17 0 0 17 39 0 6 % Q
% Arg: 0 0 6 0 0 6 28 0 23 0 6 0 0 0 0 % R
% Ser: 0 0 6 0 56 0 6 23 6 0 6 0 0 0 0 % S
% Thr: 0 6 0 0 0 0 6 0 0 6 6 0 0 6 0 % T
% Val: 6 6 28 0 0 6 23 34 0 0 0 6 6 6 17 % V
% Trp: 45 0 0 0 0 0 0 0 6 45 6 23 0 0 6 % W
% Tyr: 0 0 45 0 0 6 0 6 0 12 28 6 6 28 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _