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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TFEB
All Species:
18.18
Human Site:
S133
Identified Species:
50
UniProt:
P19484
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19484
NP_009093.1
476
52865
S133
R
A
G
H
V
L
S
S
S
A
G
N
S
A
P
Chimpanzee
Pan troglodytes
A2T713
347
38902
S91
L
L
M
Q
R
T
L
S
G
S
I
L
D
V
Y
Rhesus Macaque
Macaca mulatta
XP_001084418
490
54311
S147
R
A
G
H
V
L
S
S
S
A
G
N
S
A
P
Dog
Lupus familis
XP_851327
601
65829
S256
R
A
G
H
V
M
S
S
S
A
G
N
S
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9R210
475
52596
T132
R
A
G
H
V
L
S
T
S
A
G
N
S
A
P
Rat
Rattus norvegicus
Q63302
317
35156
L61
D
G
V
V
E
W
R
L
S
G
S
I
L
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511884
466
51479
S130
R
P
G
P
V
L
P
S
S
S
A
G
N
S
T
Chicken
Gallus gallus
Q5XFQ6
377
42496
S105
D
I
I
N
M
E
S
S
F
N
D
E
G
I
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690778
493
55390
H129
G
S
A
P
P
N
M
H
S
P
C
M
R
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.7
96.7
72.3
N.A.
93.4
34.8
N.A.
81.7
36.3
N.A.
55.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
49.5
96.7
75.2
N.A.
95.5
47.4
N.A.
87.1
52
N.A.
68.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
6.6
N.A.
40
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
6.6
N.A.
60
26.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
45
12
0
0
0
0
0
0
45
12
0
0
45
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% C
% Asp:
23
0
0
0
0
0
0
0
0
0
12
0
12
12
0
% D
% Glu:
0
0
0
0
12
12
0
0
0
0
0
12
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% F
% Gly:
12
12
56
0
0
0
0
0
12
12
45
12
12
0
12
% G
% His:
0
0
0
45
0
0
0
12
0
0
0
0
0
0
0
% H
% Ile:
0
12
12
0
0
0
0
0
0
0
12
12
0
12
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
12
12
0
0
0
45
12
12
0
0
0
12
12
0
0
% L
% Met:
0
0
12
0
12
12
12
0
0
0
0
12
0
0
0
% M
% Asn:
0
0
0
12
0
12
0
0
0
12
0
45
12
0
0
% N
% Pro:
0
12
0
23
12
0
12
0
0
12
0
0
0
0
45
% P
% Gln:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
56
0
0
0
12
0
12
0
0
0
0
0
12
0
0
% R
% Ser:
0
12
0
0
0
0
56
67
78
23
12
0
45
12
0
% S
% Thr:
0
0
0
0
0
12
0
12
0
0
0
0
0
12
12
% T
% Val:
0
0
12
12
56
0
0
0
0
0
0
0
0
12
12
% V
% Trp:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _