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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC3
All Species:
47.27
Human Site:
Y289
Identified Species:
80
UniProt:
P19447
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19447
NP_000113.1
782
89278
Y289
K
R
C
I
H
L
E
Y
P
L
L
A
E
Y
D
Chimpanzee
Pan troglodytes
XP_525907
797
91016
Y304
K
R
C
I
H
L
E
Y
P
L
L
A
E
Y
D
Rhesus Macaque
Macaca mulatta
XP_001086722
782
89213
Y289
K
R
C
I
H
L
E
Y
P
L
L
A
E
Y
D
Dog
Lupus familis
XP_533314
782
89111
Y289
K
R
C
I
H
L
E
Y
P
L
L
A
E
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
P49135
783
89108
Y290
K
R
C
I
C
L
E
Y
P
L
L
A
E
Y
D
Rat
Rattus norvegicus
Q4G005
782
89081
Y289
K
R
C
I
C
L
E
Y
P
L
L
A
E
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKK7
788
89662
Y286
K
R
C
I
H
L
D
Y
P
L
L
A
E
Y
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZVV1
782
89269
Y288
K
R
C
I
Q
L
E
Y
P
L
L
A
E
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02870
798
90330
H305
K
R
C
I
E
I
E
H
P
L
L
A
E
Y
D
Honey Bee
Apis mellifera
XP_624125
795
91356
Y305
K
R
C
I
E
L
E
Y
P
L
L
A
E
Y
D
Nematode Worm
Caenorhab. elegans
NP_499487
789
89492
Y296
K
R
C
I
E
L
E
Y
P
L
L
A
E
Y
D
Sea Urchin
Strong. purpuratus
XP_794167
745
84913
Y294
K
R
C
I
E
L
E
Y
P
L
L
A
E
Y
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FUG4
766
86717
N269
D
F
R
N
D
N
V
N
P
D
L
D
M
E
L
Baker's Yeast
Sacchar. cerevisiae
Q00578
843
95322
Y335
K
R
C
Q
E
I
D
Y
P
V
L
E
E
Y
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
99.7
97
N.A.
95.7
95.9
N.A.
N.A.
89.9
N.A.
88.6
N.A.
68.5
69.4
63.3
69.9
Protein Similarity:
100
93.5
99.7
98.7
N.A.
97.4
97.6
N.A.
N.A.
94.6
N.A.
94.6
N.A.
80.8
82.7
77.1
82.4
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
N.A.
93.3
N.A.
80
93.3
93.3
93.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
100
N.A.
93.3
N.A.
93.3
93.3
93.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.8
50.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.8
68.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
86
0
0
0
% A
% Cys:
0
0
93
0
15
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
15
0
0
8
0
8
0
0
93
% D
% Glu:
0
0
0
0
36
0
79
0
0
0
0
8
93
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
36
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
86
0
15
0
0
0
0
0
0
0
0
0
% I
% Lys:
93
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
79
0
0
0
86
100
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
8
0
8
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
93
8
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
86
0
0
0
0
0
93
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _