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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC3
All Species:
23.64
Human Site:
T756
Identified Species:
40
UniProt:
P19447
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19447
NP_000113.1
782
89278
T756
S
M
S
G
A
D
D
T
V
Y
M
E
Y
H
S
Chimpanzee
Pan troglodytes
XP_525907
797
91016
T771
S
M
S
G
A
D
D
T
V
Y
M
E
Y
H
S
Rhesus Macaque
Macaca mulatta
XP_001086722
782
89213
T756
S
M
S
G
A
D
D
T
V
Y
M
E
Y
H
S
Dog
Lupus familis
XP_533314
782
89111
T756
S
M
S
G
A
D
D
T
V
Y
M
E
Y
H
S
Cat
Felis silvestris
Mouse
Mus musculus
P49135
783
89108
T757
S
L
S
G
A
D
D
T
V
Y
M
E
Y
H
S
Rat
Rattus norvegicus
Q4G005
782
89081
T756
S
L
S
G
A
D
D
T
V
Y
M
E
Y
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKK7
788
89662
A753
S
M
S
G
A
D
D
A
V
Y
M
E
Y
H
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZVV1
782
89269
L755
M
S
G
A
D
D
A
L
Y
M
E
Y
Q
M
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02870
798
90330
G772
G
G
L
S
S
M
S
G
G
D
D
A
I
Y
Y
Honey Bee
Apis mellifera
XP_624125
795
91356
Y772
S
G
A
D
D
A
V
Y
Y
E
Y
K
K
A
P
Nematode Worm
Caenorhab. elegans
NP_499487
789
89492
A768
S
M
S
G
G
Q
G
A
Q
Y
H
S
K
A
K
Sea Urchin
Strong. purpuratus
XP_794167
745
84913
A724
L
L
Q
Q
V
L
A
A
T
D
A
D
A
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FUG4
766
86717
R732
A
M
S
G
A
N
G
R
V
Y
M
E
Y
N
S
Baker's Yeast
Sacchar. cerevisiae
Q00578
843
95322
G802
S
K
A
V
R
G
E
G
S
L
S
G
L
A
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
99.7
97
N.A.
95.7
95.9
N.A.
N.A.
89.9
N.A.
88.6
N.A.
68.5
69.4
63.3
69.9
Protein Similarity:
100
93.5
99.7
98.7
N.A.
97.4
97.6
N.A.
N.A.
94.6
N.A.
94.6
N.A.
80.8
82.7
77.1
82.4
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
N.A.
6.6
N.A.
0
6.6
33.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
6.6
N.A.
13.3
20
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.8
50.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.8
68.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
8
58
8
15
22
0
0
8
8
8
22
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
15
58
50
0
0
15
8
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
8
8
58
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
15
8
65
8
8
15
15
8
0
0
8
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
50
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
8
15
0
8
% K
% Leu:
8
22
8
0
0
8
0
8
0
8
0
0
8
0
0
% L
% Met:
8
50
0
0
0
8
0
0
0
8
58
0
0
8
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% P
% Gln:
0
0
8
8
0
8
0
0
8
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
72
8
65
8
8
0
8
0
8
0
8
8
0
0
58
% S
% Thr:
0
0
0
0
0
0
0
43
8
0
0
0
0
0
0
% T
% Val:
0
0
0
8
8
0
8
0
58
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
15
65
8
8
58
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _