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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC3
All Species:
30
Human Site:
S741
Identified Species:
50.77
UniProt:
P19447
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19447
NP_000113.1
782
89278
S741
G
S
R
S
S
Q
A
S
R
R
F
G
T
M
S
Chimpanzee
Pan troglodytes
XP_525907
797
91016
S756
G
S
R
S
S
Q
A
S
R
R
F
G
T
M
S
Rhesus Macaque
Macaca mulatta
XP_001086722
782
89213
S741
G
S
R
S
S
Q
A
S
R
R
F
G
T
M
S
Dog
Lupus familis
XP_533314
782
89111
S741
G
S
K
S
S
Q
V
S
R
R
F
G
T
M
S
Cat
Felis silvestris
Mouse
Mus musculus
P49135
783
89108
S742
G
S
R
S
G
Q
A
S
R
R
C
G
T
M
S
Rat
Rattus norvegicus
Q4G005
782
89081
S741
G
S
R
S
G
Q
A
S
R
R
F
G
T
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKK7
788
89662
S738
G
S
K
S
V
Q
M
S
R
R
T
G
T
M
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZVV1
782
89269
R740
G
G
K
P
Q
F
S
R
R
A
G
T
M
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02870
798
90330
S757
P
G
Y
R
P
S
G
S
G
G
A
V
R
R
V
Honey Bee
Apis mellifera
XP_624125
795
91356
K757
G
P
R
P
I
V
R
K
A
G
N
M
T
S
M
Nematode Worm
Caenorhab. elegans
NP_499487
789
89492
S753
A
D
G
T
I
R
I
S
R
R
E
A
T
M
A
Sea Urchin
Strong. purpuratus
XP_794167
745
84913
S709
E
Q
E
N
L
K
Y
S
T
K
Q
E
Q
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FUG4
766
86717
R717
D
G
K
A
L
K
T
R
R
S
M
G
S
M
S
Baker's Yeast
Sacchar. cerevisiae
Q00578
843
95322
S787
D
N
S
V
G
R
G
S
N
G
H
K
R
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
99.7
97
N.A.
95.7
95.9
N.A.
N.A.
89.9
N.A.
88.6
N.A.
68.5
69.4
63.3
69.9
Protein Similarity:
100
93.5
99.7
98.7
N.A.
97.4
97.6
N.A.
N.A.
94.6
N.A.
94.6
N.A.
80.8
82.7
77.1
82.4
P-Site Identity:
100
100
100
86.6
N.A.
86.6
93.3
N.A.
N.A.
73.3
N.A.
20
N.A.
6.6
20
33.3
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
80
N.A.
33.3
N.A.
6.6
20
53.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.8
50.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.8
68.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
36
0
8
8
8
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
15
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
8
0
0
0
0
0
0
0
8
8
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
36
0
0
8
0
% F
% Gly:
65
22
8
0
22
0
15
0
8
22
8
58
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
15
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
29
0
0
15
0
8
0
8
0
8
0
0
8
% K
% Leu:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
8
8
8
65
8
% M
% Asn:
0
8
0
8
0
0
0
0
8
0
8
0
0
0
0
% N
% Pro:
8
8
0
15
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
8
50
0
0
0
0
8
0
8
8
8
% Q
% Arg:
0
0
43
8
0
15
8
15
72
58
0
0
15
8
0
% R
% Ser:
0
50
8
50
29
8
8
79
0
8
0
0
8
15
65
% S
% Thr:
0
0
0
8
0
0
8
0
8
0
8
8
65
0
0
% T
% Val:
0
0
0
8
8
8
8
0
0
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _