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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC3
All Species:
26.06
Human Site:
S227
Identified Species:
44.1
UniProt:
P19447
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19447
NP_000113.1
782
89278
S227
I
S
K
T
A
E
S
S
G
G
P
S
T
S
R
Chimpanzee
Pan troglodytes
XP_525907
797
91016
S242
I
S
K
T
A
E
S
S
G
G
P
S
T
S
R
Rhesus Macaque
Macaca mulatta
XP_001086722
782
89213
S227
I
S
K
T
A
E
G
S
G
G
P
S
T
S
R
Dog
Lupus familis
XP_533314
782
89111
S227
I
A
K
T
A
E
G
S
G
G
P
S
T
S
R
Cat
Felis silvestris
Mouse
Mus musculus
P49135
783
89108
S228
S
K
T
A
A
E
G
S
G
G
P
S
T
S
Q
Rat
Rattus norvegicus
Q4G005
782
89081
S227
I
S
K
T
V
E
G
S
G
G
A
S
T
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKK7
788
89662
G224
I
S
K
S
S
E
S
G
F
G
P
S
T
S
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZVV1
782
89269
N225
I
S
K
S
Q
Q
D
N
G
G
P
S
S
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02870
798
90330
T243
P
G
A
T
D
K
P
T
P
D
P
A
A
A
A
Honey Bee
Apis mellifera
XP_624125
795
91356
T243
P
T
G
T
T
K
V
T
E
P
T
N
D
Q
V
Nematode Worm
Caenorhab. elegans
NP_499487
789
89492
A234
K
G
V
E
K
D
G
A
A
A
D
G
T
A
A
Sea Urchin
Strong. purpuratus
XP_794167
745
84913
S232
L
K
V
R
Y
E
S
S
D
S
K
D
A
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FUG4
766
86717
G212
T
S
G
E
L
E
A
G
P
G
E
L
L
N
E
Baker's Yeast
Sacchar. cerevisiae
Q00578
843
95322
T276
L
Q
Q
Q
L
Q
Q
T
A
G
K
P
A
T
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
99.7
97
N.A.
95.7
95.9
N.A.
N.A.
89.9
N.A.
88.6
N.A.
68.5
69.4
63.3
69.9
Protein Similarity:
100
93.5
99.7
98.7
N.A.
97.4
97.6
N.A.
N.A.
94.6
N.A.
94.6
N.A.
80.8
82.7
77.1
82.4
P-Site Identity:
100
100
93.3
86.6
N.A.
60
73.3
N.A.
N.A.
66.6
N.A.
53.3
N.A.
13.3
6.6
6.6
20
P-Site Similarity:
100
100
93.3
93.3
N.A.
66.6
80
N.A.
N.A.
86.6
N.A.
86.6
N.A.
40
33.3
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.8
50.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.8
68.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
36
0
8
8
15
8
8
8
22
15
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
8
8
0
8
8
8
8
8
0
0
% D
% Glu:
0
0
0
15
0
65
0
0
8
0
8
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
15
15
0
0
0
36
15
50
72
0
8
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
15
50
0
8
15
0
0
0
0
15
0
0
0
0
% K
% Leu:
15
0
0
0
15
0
0
0
0
0
0
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
8
0
8
8
% N
% Pro:
15
0
0
0
0
0
8
0
15
8
58
8
0
0
0
% P
% Gln:
0
8
8
8
8
15
8
0
0
0
0
0
0
8
29
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
29
% R
% Ser:
8
50
0
15
8
0
29
50
0
8
0
58
8
58
0
% S
% Thr:
8
8
8
50
8
0
0
22
0
0
8
0
58
8
0
% T
% Val:
0
0
15
0
8
0
8
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _