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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC1
All Species:
7.27
Human Site:
S241
Identified Species:
16
UniProt:
P18887
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18887
NP_006288
633
69526
S241
S
T
S
K
P
Q
E
S
P
K
G
K
R
K
L
Chimpanzee
Pan troglodytes
XP_512717
596
65689
A226
K
T
P
S
K
P
P
A
Q
L
S
P
S
V
P
Rhesus Macaque
Macaca mulatta
XP_001100256
645
69984
K273
K
L
G
Q
F
R
V
K
E
E
D
E
S
A
N
Dog
Lupus familis
XP_533653
654
71801
S264
S
T
S
K
P
Q
E
S
P
K
R
K
R
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q60596
631
68952
P243
S
S
S
K
P
Q
E
P
P
K
G
K
R
K
L
Rat
Rattus norvegicus
Q9ESZ0
631
68817
P243
S
S
S
K
L
Q
E
P
P
K
G
K
R
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516926
549
59237
P203
A
T
E
P
T
P
T
P
S
P
P
P
P
V
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080711
651
73244
E240
P
S
N
N
M
T
K
E
P
S
S
G
K
R
K
Zebra Danio
Brachydanio rerio
NP_001003988
615
68071
R240
T
Q
Q
A
P
V
K
R
K
F
E
F
S
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572217
614
68751
T239
A
A
S
P
K
T
S
T
S
P
S
P
V
L
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180271
512
56847
S165
S
P
K
Q
P
S
Q
S
S
T
K
R
R
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
82.3
86
N.A.
86
86.5
N.A.
47.7
N.A.
53.9
51.1
N.A.
20.7
N.A.
N.A.
38.8
Protein Similarity:
100
94.1
83
88.3
N.A.
91.1
91
N.A.
56.5
N.A.
67.7
68.8
N.A.
36.9
N.A.
N.A.
55.1
P-Site Identity:
100
6.6
0
93.3
N.A.
86.6
80
N.A.
6.6
N.A.
6.6
13.3
N.A.
6.6
N.A.
N.A.
26.6
P-Site Similarity:
100
13.3
26.6
93.3
N.A.
93.3
86.6
N.A.
13.3
N.A.
40
26.6
N.A.
20
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
0
10
0
0
0
10
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
37
10
10
10
10
10
0
0
10
% E
% Phe:
0
0
0
0
10
0
0
0
0
10
0
10
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
28
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
19
0
10
37
19
0
19
10
10
37
10
37
10
46
10
% K
% Leu:
0
10
0
0
10
0
0
0
0
10
0
0
0
19
37
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
19
% N
% Pro:
10
10
10
19
46
19
10
28
46
19
10
28
10
0
10
% P
% Gln:
0
10
10
19
0
37
10
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
10
0
0
10
10
46
10
0
% R
% Ser:
46
28
46
10
0
10
10
28
28
10
28
0
28
0
10
% S
% Thr:
10
37
0
0
10
19
10
10
0
10
0
0
0
0
10
% T
% Val:
0
0
0
0
0
10
10
0
0
0
0
0
10
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _