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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATF6 All Species: 15.76
Human Site: S364 Identified Species: 34.67
UniProt: P18850 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18850 NP_031374.2 670 74585 S364 R Q L D E V V S E N Q R L K V
Chimpanzee Pan troglodytes XP_001174215 670 74514 S364 R Q L D E V V S E N Q R L K V
Rhesus Macaque Macaca mulatta XP_001118153 620 68904 K326 R L K V P S P K R R A V C V M
Dog Lupus familis XP_545777 724 79935 S419 R Q L D E V V S E N Q R L K V
Cat Felis silvestris
Mouse Mus musculus O35451 699 75989 A380 R R L E A L L A E N S G L K L
Rat Rattus norvegicus Q5UEM7 367 40262 S73 G V S E D P G S P A P Q A P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520663 696 75605 S379 H Q L D Q V V S E N Q K L K V
Chicken Gallus gallus XP_422208 634 70203 V340 P K R R T L C V M V I L A F I
Frog Xenopus laevis NP_001088791 525 57534 G231 V V Q L P A S G I V A T Q Q V
Zebra Danio Brachydanio rerio Q502F0 428 48228 Q134 E T G F L P D Q A G G T Q C A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793757 622 68742 S328 A S D F Q T G S H A G R A L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 90.9 84.3 N.A. 33.6 21.4 N.A. 61.4 59.5 42 20.2 N.A. N.A. N.A. N.A. 23.1
Protein Similarity: 100 99.6 91.7 88.1 N.A. 50.9 35 N.A. 72.1 72.6 56.5 34.7 N.A. N.A. N.A. N.A. 43.8
P-Site Identity: 100 100 6.6 100 N.A. 40 6.6 N.A. 80 0 6.6 0 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 13.3 100 N.A. 80 26.6 N.A. 93.3 20 13.3 0 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 10 10 0 10 10 19 19 0 28 0 10 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 10 10 0 % C
% Asp: 0 0 10 37 10 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 19 28 0 0 0 46 0 0 0 0 0 0 % E
% Phe: 0 0 0 19 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 10 0 10 0 0 0 19 10 0 10 19 10 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 10 % I
% Lys: 0 10 10 0 0 0 0 10 0 0 0 10 0 46 0 % K
% Leu: 0 10 46 10 10 19 10 0 0 0 0 10 46 10 19 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 46 0 0 0 0 0 % N
% Pro: 10 0 0 0 19 19 10 0 10 0 10 0 0 10 0 % P
% Gln: 0 37 10 0 19 0 0 10 0 0 37 10 19 10 0 % Q
% Arg: 46 10 10 10 0 0 0 0 10 10 0 37 0 0 0 % R
% Ser: 0 10 10 0 0 10 10 55 0 0 10 0 0 0 10 % S
% Thr: 0 10 0 0 10 10 0 0 0 0 0 19 0 0 0 % T
% Val: 10 19 0 10 0 37 37 10 0 19 0 10 0 10 46 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _