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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMC3
All Species:
50.61
Human Site:
Y185
Identified Species:
74.22
UniProt:
P17980
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17980
NP_002795.2
439
49204
Y185
D
E
R
P
T
E
Q
Y
S
D
I
G
G
L
D
Chimpanzee
Pan troglodytes
XP_508413
555
61671
Y301
D
E
R
P
T
E
Q
Y
S
D
I
G
G
L
D
Rhesus Macaque
Macaca mulatta
XP_001106497
439
49185
Y185
D
E
R
P
T
E
Q
Y
S
D
I
G
G
L
D
Dog
Lupus familis
XP_533187
402
44931
M169
V
E
A
I
V
L
P
M
N
H
K
E
K
F
E
Cat
Felis silvestris
Mouse
Mus musculus
O88685
442
49474
Y188
D
E
R
P
T
E
Q
Y
S
D
I
G
G
L
D
Rat
Rattus norvegicus
Q63569
439
49142
Y185
D
E
R
P
T
E
Q
Y
S
D
I
G
G
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90732
440
49185
Y184
E
K
A
P
Q
E
T
Y
A
D
I
G
G
L
D
Frog
Xenopus laevis
O42586
404
45258
A166
Q
I
Q
E
L
V
E
A
I
V
L
P
M
N
H
Zebra Danio
Brachydanio rerio
NP_001002064
404
45291
A166
Q
I
Q
E
L
V
E
A
I
V
L
P
M
N
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48601
439
49305
Y183
E
K
A
P
Q
E
T
Y
A
D
I
G
G
L
D
Honey Bee
Apis mellifera
XP_392722
428
47609
Y174
D
E
R
P
T
E
Q
Y
S
D
I
G
G
L
D
Nematode Worm
Caenorhab. elegans
O16368
443
49704
Y187
E
K
A
P
Q
E
T
Y
A
D
V
G
G
L
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002330164
423
47370
Y169
D
E
K
P
T
E
D
Y
N
D
I
G
G
L
E
Maize
Zea mays
NP_001142386
430
47792
Y176
D
E
K
P
T
E
D
Y
N
D
I
G
G
L
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04019
423
47019
Y169
D
E
K
P
T
E
D
Y
N
D
I
G
G
L
E
Baker's Yeast
Sacchar. cerevisiae
P33297
434
48237
Y180
D
E
K
P
T
E
T
Y
S
D
V
G
G
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.9
99.7
91.5
N.A.
97.9
99.3
N.A.
N.A.
40
90.8
90.4
N.A.
40
83.8
39.5
N.A.
Protein Similarity:
100
79
100
91.5
N.A.
98.6
99.5
N.A.
N.A.
60.9
91.5
91.1
N.A.
60.5
91.1
59.5
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
60
0
0
N.A.
60
100
53.3
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
N.A.
80
20
20
N.A.
80
100
80
N.A.
Percent
Protein Identity:
74
75.6
N.A.
73.1
67.6
N.A.
Protein Similarity:
87
88.6
N.A.
85.4
84
N.A.
P-Site Identity:
73.3
73.3
N.A.
73.3
80
N.A.
P-Site Similarity:
93.3
93.3
N.A.
93.3
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
0
0
0
0
13
19
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
63
0
0
0
0
0
19
0
0
82
0
0
0
0
63
% D
% Glu:
19
69
0
13
0
82
13
0
0
0
0
7
0
0
25
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
82
82
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
13
% H
% Ile:
0
13
0
7
0
0
0
0
13
0
69
0
0
0
0
% I
% Lys:
0
19
25
0
0
0
0
0
0
0
7
0
7
0
0
% K
% Leu:
0
0
0
0
13
7
0
0
0
0
13
0
0
82
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
13
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
25
0
0
0
0
13
0
% N
% Pro:
0
0
0
82
0
0
7
0
0
0
0
13
0
0
0
% P
% Gln:
13
0
13
0
19
0
38
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
38
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
44
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
63
0
25
0
0
0
0
0
0
0
0
% T
% Val:
7
0
0
0
7
13
0
0
0
13
13
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _