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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMC3 All Species: 25.15
Human Site: Y132 Identified Species: 36.89
UniProt: P17980 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17980 NP_002795.2 439 49204 Y132 K T S T R Q T Y F L P V I G L
Chimpanzee Pan troglodytes XP_508413 555 61671 Y248 K T S T R Q T Y F L P V I G L
Rhesus Macaque Macaca mulatta XP_001106497 439 49185 Y132 K T S T R Q T Y F L P V I G L
Dog Lupus familis XP_533187 402 44931 I121 Q T Y F L P V I G L V D A E K
Cat Felis silvestris
Mouse Mus musculus O88685 442 49474 Y135 K T S T R Q T Y F L P V I G L
Rat Rattus norvegicus Q63569 439 49142 Y132 K T S T R Q T Y F L P V I G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90732 440 49185 H131 S T S V G S E H Y V S I L S F
Frog Xenopus laevis O42586 404 45258 Y123 V G V N K D S Y L I L E T L P
Zebra Danio Brachydanio rerio NP_001002064 404 45291 Y123 V G V N K D S Y L I L E T L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48601 439 49305 H130 S T S V G S E H Y V S I L S F
Honey Bee Apis mellifera XP_392722 428 47609 Y121 K T S T R Q T Y F L P V I G L
Nematode Worm Caenorhab. elegans O16368 443 49704 H134 S T N V G S E H Y V N I M S F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002330164 423 47370 V121 Q T I F L P V V G L V D P D K
Maize Zea mays NP_001142386 430 47792 I123 K T S T R Q T I F L P V V G L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04019 423 47019 V121 Q T I F L P V V G L V D P D T
Baker's Yeast Sacchar. cerevisiae P33297 434 48237 V127 K T S S R Q T V F L P M V G L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.9 99.7 91.5 N.A. 97.9 99.3 N.A. N.A. 40 90.8 90.4 N.A. 40 83.8 39.5 N.A.
Protein Similarity: 100 79 100 91.5 N.A. 98.6 99.5 N.A. N.A. 60.9 91.5 91.1 N.A. 60.5 91.1 59.5 N.A.
P-Site Identity: 100 100 100 13.3 N.A. 100 100 N.A. N.A. 13.3 6.6 6.6 N.A. 13.3 100 6.6 N.A.
P-Site Similarity: 100 100 100 20 N.A. 100 100 N.A. N.A. 46.6 26.6 26.6 N.A. 46.6 100 46.6 N.A.
Percent
Protein Identity: 74 75.6 N.A. 73.1 67.6 N.A.
Protein Similarity: 87 88.6 N.A. 85.4 84 N.A.
P-Site Identity: 13.3 86.6 N.A. 13.3 73.3 N.A.
P-Site Similarity: 20 93.3 N.A. 20 93.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 13 0 0 0 0 0 19 0 13 0 % D
% Glu: 0 0 0 0 0 0 19 0 0 0 0 13 0 7 0 % E
% Phe: 0 0 0 19 0 0 0 0 50 0 0 0 0 0 19 % F
% Gly: 0 13 0 0 19 0 0 0 19 0 0 0 0 50 0 % G
% His: 0 0 0 0 0 0 0 19 0 0 0 0 0 0 0 % H
% Ile: 0 0 13 0 0 0 0 13 0 13 0 19 38 0 0 % I
% Lys: 50 0 0 0 13 0 0 0 0 0 0 0 0 0 13 % K
% Leu: 0 0 0 0 19 0 0 0 13 69 13 0 13 13 50 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % M
% Asn: 0 0 7 13 0 0 0 0 0 0 7 0 0 0 0 % N
% Pro: 0 0 0 0 0 19 0 0 0 0 50 0 13 0 13 % P
% Gln: 19 0 0 0 0 50 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 50 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 19 0 63 7 0 19 13 0 0 0 13 0 0 19 0 % S
% Thr: 0 88 0 44 0 0 50 0 0 0 0 0 13 0 7 % T
% Val: 13 0 13 19 0 0 19 19 0 19 19 44 13 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 50 19 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _