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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMC3
All Species:
22.73
Human Site:
T63
Identified Species:
33.33
UniProt:
P17980
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17980
NP_002795.2
439
49204
T63
K
S
E
V
L
R
V
T
H
E
L
Q
A
M
K
Chimpanzee
Pan troglodytes
XP_508413
555
61671
T179
K
S
E
V
L
R
V
T
H
E
L
Q
A
M
K
Rhesus Macaque
Macaca mulatta
XP_001106497
439
49185
T63
K
S
E
V
L
R
V
T
H
E
L
Q
A
M
K
Dog
Lupus familis
XP_533187
402
44931
S61
K
D
K
I
K
E
N
S
E
K
I
K
V
N
K
Cat
Felis silvestris
Mouse
Mus musculus
O88685
442
49474
T66
K
S
E
V
L
R
V
T
H
E
L
Q
A
M
K
Rat
Rattus norvegicus
Q63569
439
49142
T63
K
S
E
V
L
R
V
T
H
E
L
Q
A
M
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90732
440
49185
K69
L
L
K
L
E
R
I
K
D
Y
L
L
M
E
E
Frog
Xenopus laevis
O42586
404
45258
D63
S
N
V
I
E
L
L
D
V
D
P
N
D
Q
E
Zebra Danio
Brachydanio rerio
NP_001002064
404
45291
D63
S
N
V
I
E
L
L
D
V
D
P
N
D
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48601
439
49305
I67
K
L
L
K
L
E
R
I
K
D
Y
L
M
M
E
Honey Bee
Apis mellifera
XP_392722
428
47609
D59
H
E
L
Q
A
Q
N
D
K
I
K
E
N
T
E
Nematode Worm
Caenorhab. elegans
O16368
443
49704
Y74
K
S
E
R
I
K
D
Y
L
L
M
E
Q
E
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002330164
423
47370
Q60
K
E
K
I
K
E
N
Q
E
K
I
K
L
N
K
Maize
Zea mays
NP_001142386
430
47792
K60
N
L
E
L
E
S
F
K
E
K
I
K
E
N
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04019
423
47019
Q60
K
E
K
I
K
E
N
Q
E
K
I
K
L
N
K
Baker's Yeast
Sacchar. cerevisiae
P33297
434
48237
L59
S
H
E
N
N
V
M
L
E
K
I
K
D
N
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.9
99.7
91.5
N.A.
97.9
99.3
N.A.
N.A.
40
90.8
90.4
N.A.
40
83.8
39.5
N.A.
Protein Similarity:
100
79
100
91.5
N.A.
98.6
99.5
N.A.
N.A.
60.9
91.5
91.1
N.A.
60.5
91.1
59.5
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
13.3
0
0
N.A.
20
0
20
N.A.
P-Site Similarity:
100
100
100
53.3
N.A.
100
100
N.A.
N.A.
40
33.3
33.3
N.A.
33.3
20
46.6
N.A.
Percent
Protein Identity:
74
75.6
N.A.
73.1
67.6
N.A.
Protein Similarity:
87
88.6
N.A.
85.4
84
N.A.
P-Site Identity:
13.3
6.6
N.A.
13.3
13.3
N.A.
P-Site Similarity:
46.6
40
N.A.
46.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
0
0
0
0
32
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
7
19
7
19
0
0
19
0
0
% D
% Glu:
0
19
50
0
25
25
0
0
32
32
0
13
7
13
32
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
7
7
0
0
0
0
0
0
32
0
0
0
0
0
0
% H
% Ile:
0
0
0
32
7
0
7
7
0
7
32
0
0
0
0
% I
% Lys:
63
0
25
7
19
7
0
13
13
32
7
32
0
0
57
% K
% Leu:
7
19
13
13
38
13
13
7
7
7
38
13
13
0
0
% L
% Met:
0
0
0
0
0
0
7
0
0
0
7
0
13
38
0
% M
% Asn:
7
13
0
7
7
0
25
0
0
0
0
13
7
32
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% P
% Gln:
0
0
0
7
0
7
0
13
0
0
0
32
7
13
7
% Q
% Arg:
0
0
0
7
0
38
7
0
0
0
0
0
0
0
0
% R
% Ser:
19
38
0
0
0
7
0
7
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
32
0
0
0
0
0
7
0
% T
% Val:
0
0
13
32
0
7
32
0
13
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
7
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _