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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMC3 All Species: 45.76
Human Site: T166 Identified Species: 67.11
UniProt: P17980 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17980 NP_002795.2 439 49204 T166 L I L E T L P T E Y D S R V K
Chimpanzee Pan troglodytes XP_508413 555 61671 T282 L I L E T L P T E Y D S R V K
Rhesus Macaque Macaca mulatta XP_001106497 439 49185 T166 L I L E T L P T E Y D S R V K
Dog Lupus familis XP_533187 402 44931 T150 L I L E T L P T E Y D S R V K
Cat Felis silvestris
Mouse Mus musculus O88685 442 49474 T169 L I L E T L P T D Y D S R V K
Rat Rattus norvegicus Q63569 439 49142 T166 L I L E T L P T E Y D S R V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90732 440 49185 D165 A V I G V L M D D T D P L V T
Frog Xenopus laevis O42586 404 45258 T147 M E V D E R P T E Q Y S D I G
Zebra Danio Brachydanio rerio NP_001002064 404 45291 T147 M E V D E R P T E Q Y S D I G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48601 439 49305 D164 A V V G V L S D D T D P M V T
Honey Bee Apis mellifera XP_392722 428 47609 A155 L V L E T L P A E Y D A R V K
Nematode Worm Caenorhab. elegans O16368 443 49704 D168 A V I G V L S D D T D P M V S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002330164 423 47370 S150 L I L D T L P S E Y D S R V K
Maize Zea mays NP_001142386 430 47792 S157 L I L D T L P S E Y D S R V K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04019 423 47019 S150 L I L D T L P S E Y D S R V K
Baker's Yeast Sacchar. cerevisiae P33297 434 48237 S161 L I L D T L P S E F D S R V K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.9 99.7 91.5 N.A. 97.9 99.3 N.A. N.A. 40 90.8 90.4 N.A. 40 83.8 39.5 N.A.
Protein Similarity: 100 79 100 91.5 N.A. 98.6 99.5 N.A. N.A. 60.9 91.5 91.1 N.A. 60.5 91.1 59.5 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. N.A. 20 26.6 26.6 N.A. 20 80 20 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 40 53.3 53.3 N.A. 40 93.3 40 N.A.
Percent
Protein Identity: 74 75.6 N.A. 73.1 67.6 N.A.
Protein Similarity: 87 88.6 N.A. 85.4 84 N.A.
P-Site Identity: 86.6 86.6 N.A. 86.6 80 N.A.
P-Site Similarity: 100 100 N.A. 100 100 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 38 0 0 0 19 25 0 88 0 13 0 0 % D
% Glu: 0 13 0 44 13 0 0 0 75 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % F
% Gly: 0 0 0 19 0 0 0 0 0 0 0 0 0 0 13 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 63 13 0 0 0 0 0 0 0 0 0 0 13 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 69 % K
% Leu: 69 0 69 0 0 88 0 0 0 0 0 0 7 0 0 % L
% Met: 13 0 0 0 0 0 7 0 0 0 0 0 13 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 82 0 0 0 0 19 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 13 0 0 0 0 0 0 69 0 0 % R
% Ser: 0 0 0 0 0 0 13 25 0 0 0 75 0 0 7 % S
% Thr: 0 0 0 0 69 0 0 50 0 19 0 0 0 0 13 % T
% Val: 0 25 19 0 19 0 0 0 0 0 0 0 0 88 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 63 13 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _