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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMC3 All Species: 20
Human Site: S37 Identified Species: 29.33
UniProt: P17980 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17980 NP_002795.2 439 49204 S37 G E E V L K M S T E E I I Q R
Chimpanzee Pan troglodytes XP_508413 555 61671 S153 G E E V L K M S T E E I I Q R
Rhesus Macaque Macaca mulatta XP_001106497 439 49185 S37 G E E V L K M S T E E I I Q R
Dog Lupus familis XP_533187 402 44931 E35 R T R L L D S E I K I M K S E
Cat Felis silvestris
Mouse Mus musculus O88685 442 49474 S40 G E E V L K M S T E E I V Q R
Rat Rattus norvegicus Q63569 439 49142 S37 G E E V L K M S T E E I V Q R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90732 440 49185 P43 K K K K T K G P D A A S K P P
Frog Xenopus laevis O42586 404 45258 K37 E L Q A M R D K I K E N S E K
Zebra Danio Brachydanio rerio NP_001002064 404 45291 K37 E L Q A M K D K I K E N T E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48601 439 49305 G41 K K K R R A K G P D A A M K L
Honey Bee Apis mellifera XP_392722 428 47609 T33 T D E I V S R T R L L D N E I
Nematode Worm Caenorhab. elegans O16368 443 49704 A48 K G S K G P D A A S K L P A V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002330164 423 47370 E34 G S R L V D N E I R I L K E E
Maize Zea mays NP_001142386 430 47792 A34 S T E D I I R A S R L L D N E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04019 423 47019 E34 A S R L L A N E I R I L K E E
Baker's Yeast Sacchar. cerevisiae P33297 434 48237 R33 S T Q E L Q T R A K L L D N E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.9 99.7 91.5 N.A. 97.9 99.3 N.A. N.A. 40 90.8 90.4 N.A. 40 83.8 39.5 N.A.
Protein Similarity: 100 79 100 91.5 N.A. 98.6 99.5 N.A. N.A. 60.9 91.5 91.1 N.A. 60.5 91.1 59.5 N.A.
P-Site Identity: 100 100 100 6.6 N.A. 93.3 93.3 N.A. N.A. 6.6 6.6 13.3 N.A. 0 6.6 0 N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 100 100 N.A. N.A. 20 46.6 46.6 N.A. 33.3 40 20 N.A.
Percent
Protein Identity: 74 75.6 N.A. 73.1 67.6 N.A.
Protein Similarity: 87 88.6 N.A. 85.4 84 N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 6.6 N.A.
P-Site Similarity: 33.3 33.3 N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 13 0 13 0 13 13 7 13 7 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 7 0 13 19 0 7 7 0 7 13 0 0 % D
% Glu: 13 32 44 7 0 0 0 19 0 32 44 0 0 32 32 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 38 7 0 0 7 0 7 7 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 7 7 0 0 32 0 19 32 19 0 7 % I
% Lys: 19 13 13 13 0 44 7 13 0 25 7 0 25 7 13 % K
% Leu: 0 13 0 19 50 0 0 0 0 7 19 32 0 0 7 % L
% Met: 0 0 0 0 13 0 32 0 0 0 0 7 7 0 0 % M
% Asn: 0 0 0 0 0 0 13 0 0 0 0 13 7 13 0 % N
% Pro: 0 0 0 0 0 7 0 7 7 0 0 0 7 7 7 % P
% Gln: 0 0 19 0 0 7 0 0 0 0 0 0 0 32 0 % Q
% Arg: 7 0 19 7 7 7 13 7 7 19 0 0 0 0 32 % R
% Ser: 13 13 7 0 0 7 7 32 7 7 0 7 7 7 0 % S
% Thr: 7 19 0 0 7 0 7 7 32 0 0 0 7 0 0 % T
% Val: 0 0 0 32 13 0 0 0 0 0 0 0 13 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _