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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IGFBP3 All Species: 25.15
Human Site: T85 Identified Species: 61.48
UniProt: P17936 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17936 NP_000589.2 291 31674 T85 G Q P C G I Y T E R C G S G L
Chimpanzee Pan troglodytes XP_511475 258 27929 T58 P G C G C C A T C A L G L G M
Rhesus Macaque Macaca mulatta XP_001085359 291 31575 T85 G Q P C G I Y T E R C G S G L
Dog Lupus familis XP_548740 563 59524 T359 G Q P C G V Y T E R C G A G L
Cat Felis silvestris
Mouse Mus musculus P47878 291 31701 T86 G D A C G V Y T E R C G T G L
Rat Rattus norvegicus P15473 292 31661 T87 G D A C G V Y T E R C G T G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507772 210 23181 A11 G L L A L W P A L A L T L L S
Chicken Gallus gallus P49705 311 33520 T88 D E A C G V Y T P R C A A G L
Frog Xenopus laevis Q90WV8 265 29976 A63 C C M T C A L A E G H R C G V
Zebra Danio Brachydanio rerio Q9PTH3 276 30746 T73 G E Q C G V Y T P R C S S G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35 98.6 42 N.A. 79.3 82.1 N.A. 52.9 32.7 40.8 31.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 47.7 99.6 45.6 N.A. 86.2 87.6 N.A. 58.7 45.9 56 45.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 100 86.6 N.A. 73.3 73.3 N.A. 6.6 53.3 13.3 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 86.6 86.6 N.A. 6.6 73.3 20 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 30 10 0 10 10 20 0 20 0 10 20 0 0 % A
% Cys: 10 10 10 70 20 10 0 0 10 0 70 0 10 0 0 % C
% Asp: 10 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 20 0 0 0 0 0 0 60 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 70 10 0 10 70 0 0 0 0 10 0 60 0 90 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 10 0 10 0 10 0 10 0 20 0 20 10 70 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 30 0 0 0 10 0 20 0 0 0 0 0 0 % P
% Gln: 0 30 10 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 70 0 10 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 10 30 0 10 % S
% Thr: 0 0 0 10 0 0 0 80 0 0 0 10 20 0 0 % T
% Val: 0 0 0 0 0 50 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 70 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _