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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TAT
All Species:
36.67
Human Site:
Y186
Identified Species:
62.05
UniProt:
P17735
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17735
NP_000344.1
454
50399
Y186
M
G
I
E
V
K
L
Y
N
L
L
P
E
K
S
Chimpanzee
Pan troglodytes
XP_511091
454
50273
Y186
M
G
I
E
V
K
L
Y
N
L
L
P
E
K
S
Rhesus Macaque
Macaca mulatta
XP_001106194
454
50404
Y186
M
G
I
E
V
K
L
Y
N
L
L
P
E
K
S
Dog
Lupus familis
XP_536796
454
50314
Y186
M
G
I
E
V
K
L
Y
N
L
L
P
E
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZR1
454
50547
Y186
M
G
I
E
V
K
L
Y
N
L
L
P
E
K
S
Rat
Rattus norvegicus
P04694
454
50617
Y186
M
G
I
E
V
K
L
Y
N
L
L
P
E
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509220
455
50659
Y186
M
G
I
E
V
K
L
Y
N
L
L
P
E
R
S
Chicken
Gallus gallus
XP_414240
455
50533
Y186
M
G
I
E
V
K
L
Y
N
L
M
P
E
K
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7T3E5
450
50327
T183
L
R
L
K
S
T
A
T
T
G
I
S
S
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572953
501
55910
Y226
L
D
I
E
V
R
Y
Y
D
L
L
P
D
Q
Q
Honey Bee
Apis mellifera
XP_001121079
425
47891
D175
D
D
L
E
S
Q
I
D
E
S
T
A
A
I
V
Nematode Worm
Caenorhab. elegans
NP_510454
464
51013
K190
N
I
V
D
K
P
Y
K
I
D
M
T
G
E
D
Sea Urchin
Strong. purpuratus
XP_796747
395
43489
E165
L
M
P
C
K
S
W
E
V
D
L
E
N
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47039
444
50064
Q176
N
P
P
K
E
L
D
Q
R
N
T
R
G
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.1
93.1
N.A.
92
91.6
N.A.
88.1
81.9
N.A.
20.2
N.A.
44.3
51.7
41.3
48.9
Protein Similarity:
100
99.7
98.4
96.6
N.A.
96.6
96
N.A.
94.9
91.8
N.A.
41.4
N.A.
63
67.1
60.9
64.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
0
N.A.
46.6
6.6
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
26.6
N.A.
80
26.6
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
0
0
8
8
8
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
0
8
0
0
8
8
8
15
0
0
8
0
15
% D
% Glu:
0
0
0
72
8
0
0
8
8
0
0
8
58
15
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
58
0
0
0
0
0
0
0
8
0
0
15
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
65
0
0
0
8
0
8
0
8
0
0
8
0
% I
% Lys:
0
0
0
15
15
58
0
8
0
0
0
0
0
50
0
% K
% Leu:
22
0
15
0
0
8
58
0
0
65
65
0
0
8
0
% L
% Met:
58
8
0
0
0
0
0
0
0
0
15
0
0
0
0
% M
% Asn:
15
0
0
0
0
0
0
0
58
8
0
0
8
0
0
% N
% Pro:
0
8
15
0
0
8
0
0
0
0
0
65
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
8
0
0
0
0
0
8
8
% Q
% Arg:
0
8
0
0
0
8
0
0
8
0
0
8
0
8
0
% R
% Ser:
0
0
0
0
15
8
0
0
0
8
0
8
8
0
58
% S
% Thr:
0
0
0
0
0
8
0
8
8
0
15
8
0
0
0
% T
% Val:
0
0
8
0
65
0
0
0
8
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
15
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _