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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TAT
All Species:
35.45
Human Site:
Y106
Identified Species:
60
UniProt:
P17735
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17735
NP_000344.1
454
50399
Y106
D
A
L
D
S
G
K
Y
N
G
Y
A
P
S
I
Chimpanzee
Pan troglodytes
XP_511091
454
50273
Y106
D
A
L
D
S
G
K
Y
N
G
Y
A
P
S
I
Rhesus Macaque
Macaca mulatta
XP_001106194
454
50404
Y106
D
A
L
D
S
G
K
Y
N
G
Y
A
P
S
I
Dog
Lupus familis
XP_536796
454
50314
Y106
D
A
L
D
S
G
K
Y
N
G
Y
A
P
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZR1
454
50547
Y106
D
A
L
D
S
G
K
Y
N
G
Y
A
P
S
I
Rat
Rattus norvegicus
P04694
454
50617
Y106
D
A
L
D
S
G
K
Y
N
G
Y
A
P
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509220
455
50659
Y106
D
A
L
D
S
G
K
Y
N
G
Y
A
P
S
I
Chicken
Gallus gallus
XP_414240
455
50533
Y106
E
A
L
D
S
G
R
Y
N
G
Y
A
P
S
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7T3E5
450
50327
V111
L
V
K
A
L
S
K
V
Y
G
K
V
Y
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572953
501
55910
Y144
H
S
L
E
S
G
K
Y
N
G
Y
A
S
T
Q
Honey Bee
Apis mellifera
XP_001121079
425
47891
A104
N
E
F
V
K
V
D
A
K
D
V
I
L
C
S
Nematode Worm
Caenorhab. elegans
NP_510454
464
51013
F109
E
S
V
S
S
H
M
F
D
G
Y
G
P
A
V
Sea Urchin
Strong. purpuratus
XP_796747
395
43489
K95
A
R
A
A
V
A
K
K
Y
S
H
P
D
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47039
444
50064
L101
R
P
S
L
I
N
S
L
I
K
L
Y
S
P
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.1
93.1
N.A.
92
91.6
N.A.
88.1
81.9
N.A.
20.2
N.A.
44.3
51.7
41.3
48.9
Protein Similarity:
100
99.7
98.4
96.6
N.A.
96.6
96
N.A.
94.9
91.8
N.A.
41.4
N.A.
63
67.1
60.9
64.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
80
N.A.
13.3
N.A.
60
0
26.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
N.A.
80
6.6
73.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
58
8
15
0
8
0
8
0
0
0
65
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
50
0
0
58
0
0
8
0
8
8
0
0
8
8
0
% D
% Glu:
15
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
65
0
0
0
79
0
8
0
0
0
% G
% His:
8
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
8
0
0
8
0
0
58
% I
% Lys:
0
0
8
0
8
0
72
8
8
8
8
0
0
0
0
% K
% Leu:
8
0
65
8
8
0
0
8
0
0
8
0
8
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
8
0
0
65
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
8
65
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
8
8
0
0
0
0
8
0
0
0
0
0
0
0
8
% R
% Ser:
0
15
8
8
72
8
8
0
0
8
0
0
15
58
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
8
8
8
8
8
0
8
0
0
8
8
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
15
0
72
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _