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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAT All Species: 39.09
Human Site: S313 Identified Species: 66.15
UniProt: P17735 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17735 NP_000344.1 454 50399 S313 R D G L V K L S Q R I L G P C
Chimpanzee Pan troglodytes XP_511091 454 50273 S313 R D G L V K L S Q R I L G P C
Rhesus Macaque Macaca mulatta XP_001106194 454 50404 S313 R D G L A K L S Q R I L G P C
Dog Lupus familis XP_536796 454 50314 S313 R D G L V K L S Q R I L G P C
Cat Felis silvestris
Mouse Mus musculus Q8QZR1 454 50547 S313 R D G L V K L S Q R I L G P C
Rat Rattus norvegicus P04694 454 50617 S313 R D G L V K L S Q R I L G P C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509220 455 50659 T313 R D G L V K L T Q R I L G P C
Chicken Gallus gallus XP_414240 455 50533 S313 R D G L I R L S Q R I L G P C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7T3E5 450 50327 T310 V M Q N S L Y T C P T P L Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572953 501 55910 C352 I V G L K N M C G R I L G S N
Honey Bee Apis mellifera XP_001121079 425 47891 S280 E V A L H C L S Q R I I G S N
Nematode Worm Caenorhab. elegans NP_510454 464 51013 S316 K N G I V A L S Q K I V G P C
Sea Urchin Strong. purpuratus XP_796747 395 43489 G260 L A P G W R L G W I L V H D P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47039 444 50064 T299 S Y A A K A H T R I C F A S P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97.1 93.1 N.A. 92 91.6 N.A. 88.1 81.9 N.A. 20.2 N.A. 44.3 51.7 41.3 48.9
Protein Similarity: 100 99.7 98.4 96.6 N.A. 96.6 96 N.A. 94.9 91.8 N.A. 41.4 N.A. 63 67.1 60.9 64.5
P-Site Identity: 100 100 93.3 100 N.A. 100 100 N.A. 93.3 86.6 N.A. 0 N.A. 40 46.6 60 6.6
P-Site Similarity: 100 100 93.3 100 N.A. 100 100 N.A. 100 100 N.A. 6.6 N.A. 46.6 53.3 93.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 39.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 15 8 8 15 0 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 8 0 8 8 0 8 0 0 0 65 % C
% Asp: 0 58 0 0 0 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 72 8 0 0 0 8 8 0 0 0 79 0 0 % G
% His: 0 0 0 0 8 0 8 0 0 0 0 0 8 0 0 % H
% Ile: 8 0 0 8 8 0 0 0 0 15 79 8 0 0 0 % I
% Lys: 8 0 0 0 15 50 0 0 0 8 0 0 0 0 0 % K
% Leu: 8 0 0 72 0 8 79 0 0 0 8 65 8 0 0 % L
% Met: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 8 0 8 0 0 0 0 0 0 0 0 15 % N
% Pro: 0 0 8 0 0 0 0 0 0 8 0 8 0 65 15 % P
% Gln: 0 0 8 0 0 0 0 0 72 0 0 0 0 8 0 % Q
% Arg: 58 0 0 0 0 15 0 0 8 72 0 0 0 0 0 % R
% Ser: 8 0 0 0 8 0 0 65 0 0 0 0 0 22 0 % S
% Thr: 0 0 0 0 0 0 0 22 0 0 8 0 0 0 0 % T
% Val: 8 15 0 0 50 0 0 0 0 0 0 15 0 0 0 % V
% Trp: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _