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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TAT
All Species:
35.15
Human Site:
S223
Identified Species:
59.49
UniProt:
P17735
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17735
NP_000344.1
454
50399
S223
N
P
S
N
P
C
G
S
V
F
S
K
R
H
L
Chimpanzee
Pan troglodytes
XP_511091
454
50273
S223
N
P
S
N
P
C
G
S
V
F
S
K
R
H
L
Rhesus Macaque
Macaca mulatta
XP_001106194
454
50404
S223
N
P
S
N
P
C
G
S
V
F
S
K
R
H
L
Dog
Lupus familis
XP_536796
454
50314
S223
N
P
S
N
P
C
G
S
V
F
S
K
S
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZR1
454
50547
S223
N
P
S
N
P
C
G
S
V
F
S
K
R
H
L
Rat
Rattus norvegicus
P04694
454
50617
S223
N
P
S
N
P
C
G
S
V
F
S
K
R
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509220
455
50659
S223
N
P
S
N
P
C
G
S
V
F
S
R
S
H
L
Chicken
Gallus gallus
XP_414240
455
50533
S223
N
P
S
N
P
C
G
S
V
F
S
K
S
H
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7T3E5
450
50327
K220
T
P
N
N
P
I
G
K
I
F
S
R
S
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572953
501
55910
S263
N
P
S
N
P
C
G
S
V
F
D
E
K
H
L
Honey Bee
Apis mellifera
XP_001121079
425
47891
P212
V
A
A
R
Y
Y
V
P
I
I
A
D
E
I
Y
Nematode Worm
Caenorhab. elegans
NP_510454
464
51013
G227
N
P
G
N
P
T
G
G
V
F
T
K
E
H
L
Sea Urchin
Strong. purpuratus
XP_796747
395
43489
D202
F
S
K
E
H
I
Q
D
I
I
K
I
A
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47039
444
50064
K213
T
P
H
N
P
I
G
K
V
F
T
R
E
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.1
93.1
N.A.
92
91.6
N.A.
88.1
81.9
N.A.
20.2
N.A.
44.3
51.7
41.3
48.9
Protein Similarity:
100
99.7
98.4
96.6
N.A.
96.6
96
N.A.
94.9
91.8
N.A.
41.4
N.A.
63
67.1
60.9
64.5
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
86.6
93.3
N.A.
46.6
N.A.
80
0
66.6
0
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
93.3
93.3
N.A.
66.6
N.A.
93.3
20
73.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
0
0
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
65
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
8
8
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
8
22
15
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
86
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
86
8
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
8
0
0
0
0
0
0
0
0
72
0
% H
% Ile:
0
0
0
0
0
22
0
0
22
15
0
8
0
8
0
% I
% Lys:
0
0
8
0
0
0
0
15
0
0
8
58
8
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
86
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
72
0
8
86
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
86
0
0
86
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
22
36
0
0
% R
% Ser:
0
8
65
0
0
0
0
65
0
0
65
0
29
8
0
% S
% Thr:
15
0
0
0
0
8
0
0
0
0
15
0
0
0
0
% T
% Val:
8
0
0
0
0
0
8
0
79
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _