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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAT All Species: 34.24
Human Site: S112 Identified Species: 57.95
UniProt: P17735 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17735 NP_000344.1 454 50399 S112 K Y N G Y A P S I G F L S S R
Chimpanzee Pan troglodytes XP_511091 454 50273 S112 K Y N G Y A P S I G F L S S R
Rhesus Macaque Macaca mulatta XP_001106194 454 50404 S112 K Y N G Y A P S I G F L S S R
Dog Lupus familis XP_536796 454 50314 S112 K Y N G Y A P S I G Y L S S R
Cat Felis silvestris
Mouse Mus musculus Q8QZR1 454 50547 S112 K Y N G Y A P S I G Y L S S R
Rat Rattus norvegicus P04694 454 50617 S112 K Y N G Y A P S I G Y L S S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509220 455 50659 S112 K Y N G Y A P S I G Y L S S R
Chicken Gallus gallus XP_414240 455 50533 S112 R Y N G Y A P S V G Y Q S C R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7T3E5 450 50327 D117 K V Y G K V Y D R Q L D P F K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572953 501 55910 T150 K Y N G Y A S T Q G H E I A R
Honey Bee Apis mellifera XP_001121079 425 47891 C110 D A K D V I L C S G C S C A L
Nematode Worm Caenorhab. elegans NP_510454 464 51013 A115 M F D G Y G P A V G A L A A R
Sea Urchin Strong. purpuratus XP_796747 395 43489 A101 K K Y S H P D A P L T S E D V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47039 444 50064 P107 S L I K L Y S P I Y N T E L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97.1 93.1 N.A. 92 91.6 N.A. 88.1 81.9 N.A. 20.2 N.A. 44.3 51.7 41.3 48.9
Protein Similarity: 100 99.7 98.4 96.6 N.A. 96.6 96 N.A. 94.9 91.8 N.A. 41.4 N.A. 63 67.1 60.9 64.5
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 93.3 66.6 N.A. 13.3 N.A. 53.3 6.6 40 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 86.6 N.A. 20 N.A. 66.6 13.3 80 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 39.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 65 0 15 0 0 8 0 8 22 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 8 0 8 8 0 % C
% Asp: 8 0 8 8 0 0 8 8 0 0 0 8 0 8 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 8 15 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 22 0 0 8 0 % F
% Gly: 0 0 0 79 0 8 0 0 0 79 0 0 0 0 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 8 0 0 8 0 0 58 0 0 0 8 0 0 % I
% Lys: 72 8 8 8 8 0 0 0 0 0 0 0 0 0 15 % K
% Leu: 0 8 0 0 8 0 8 0 0 8 8 58 0 8 8 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 65 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 8 65 8 8 0 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 8 0 8 0 0 0 % Q
% Arg: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 72 % R
% Ser: 8 0 0 8 0 0 15 58 8 0 0 15 58 50 0 % S
% Thr: 0 0 0 0 0 0 0 8 0 0 8 8 0 0 0 % T
% Val: 0 8 0 0 8 8 0 0 15 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 65 15 0 72 8 8 0 0 8 36 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _