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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRISP2
All Species:
14.24
Human Site:
S216
Identified Species:
39.17
UniProt:
P16562
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16562
NP_001135879.1
243
27259
S216
D
L
L
S
N
C
D
S
L
K
N
T
A
G
C
Chimpanzee
Pan troglodytes
XP_518530
243
27244
S216
D
L
L
S
N
C
D
S
L
K
N
T
A
G
C
Rhesus Macaque
Macaca mulatta
Q9XSD3
249
28634
L222
D
E
Y
T
D
C
S
L
E
V
R
F
L
G
C
Dog
Lupus familis
XP_852687
244
27240
S217
D
L
L
S
N
C
D
S
L
K
K
T
A
G
C
Cat
Felis silvestris
Mouse
Mus musculus
P16563
243
27587
S216
D
L
L
S
N
C
E
S
L
K
T
S
A
G
C
Rat
Rattus norvegicus
P12020
246
27829
L220
N
Y
S
N
C
G
D
L
K
K
M
V
S
C
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509451
233
26465
L207
E
Y
S
N
C
P
D
L
A
K
N
P
G
C
D
Chicken
Gallus gallus
XP_420051
170
18975
S144
T
Q
L
V
W
Y
N
S
Y
Q
V
G
C
A
V
Frog
Xenopus laevis
NP_001082594
241
26932
N214
D
L
Y
T
G
C
S
N
F
I
A
Y
C
N
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
44.1
81.9
N.A.
70.3
54
N.A.
49.3
39.5
41.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
59.8
91.8
N.A.
85.5
69.1
N.A.
65
49.3
58.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
26.6
93.3
N.A.
80
13.3
N.A.
20
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
40
93.3
N.A.
93.3
33.3
N.A.
33.3
26.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
12
0
12
0
45
12
0
% A
% Cys:
0
0
0
0
23
67
0
0
0
0
0
0
23
23
56
% C
% Asp:
67
0
0
0
12
0
56
0
0
0
0
0
0
0
23
% D
% Glu:
12
12
0
0
0
0
12
0
12
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
0
12
0
0
0
% F
% Gly:
0
0
0
0
12
12
0
0
0
0
0
12
12
56
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
12
% I
% Lys:
0
0
0
0
0
0
0
0
12
67
12
0
0
0
0
% K
% Leu:
0
56
56
0
0
0
0
34
45
0
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% M
% Asn:
12
0
0
23
45
0
12
12
0
0
34
0
0
12
0
% N
% Pro:
0
0
0
0
0
12
0
0
0
0
0
12
0
0
0
% P
% Gln:
0
12
0
0
0
0
0
0
0
12
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% R
% Ser:
0
0
23
45
0
0
23
56
0
0
0
12
12
0
0
% S
% Thr:
12
0
0
23
0
0
0
0
0
0
12
34
0
0
0
% T
% Val:
0
0
0
12
0
0
0
0
0
12
12
12
0
0
12
% V
% Trp:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
23
23
0
0
12
0
0
12
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _