KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3CB
All Species:
42.73
Human Site:
Y267
Identified Species:
67.14
UniProt:
P16298
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16298
NP_001135826.1
524
59024
Y267
N
T
V
R
G
C
S
Y
F
Y
N
Y
P
A
V
Chimpanzee
Pan troglodytes
XP_001142700
534
60207
Y267
N
T
V
R
G
C
S
Y
F
Y
N
Y
P
A
V
Rhesus Macaque
Macaca mulatta
XP_001101616
524
59006
Y267
N
T
V
R
G
C
S
Y
F
Y
N
Y
P
A
V
Dog
Lupus familis
XP_850935
524
59010
Y267
N
T
V
R
G
C
S
Y
F
Y
N
Y
P
A
V
Cat
Felis silvestris
Mouse
Mus musculus
P48453
525
59155
Y267
N
T
V
R
G
C
S
Y
F
Y
N
Y
P
A
V
Rat
Rattus norvegicus
P20651
525
59095
Y267
N
T
V
R
G
C
S
Y
F
Y
N
Y
P
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505489
437
49430
A201
N
L
L
S
I
I
R
A
H
E
A
Q
D
A
G
Chicken
Gallus gallus
P48463
309
35545
K74
E
L
F
R
I
G
G
K
S
P
D
T
N
Y
L
Frog
Xenopus laevis
NP_001080813
518
58366
Y258
N
T
V
R
G
C
S
Y
F
Y
S
Y
P
A
V
Zebra Danio
Brachydanio rerio
NP_001017856
511
57796
Y247
N
T
V
R
G
C
S
Y
F
Y
S
Y
P
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27889
570
63082
Y324
N
S
V
R
G
C
S
Y
F
Y
S
Y
A
A
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTT8
321
36288
N86
G
G
S
P
P
N
T
N
Y
L
F
L
G
D
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48486
322
36548
L87
P
A
A
N
Y
L
F
L
G
D
Y
V
D
R
G
Baker's Yeast
Sacchar. cerevisiae
P14747
604
68509
Y336
N
S
V
R
G
C
S
Y
A
F
T
Y
R
A
A
Red Bread Mold
Neurospora crassa
Q05681
558
63895
Y296
N
H
V
R
G
C
S
Y
F
F
S
Y
S
A
A
Conservation
Percent
Protein Identity:
100
98.1
99.6
99.6
N.A.
99
98.8
N.A.
81.8
27.6
81.8
81.4
N.A.
69.4
N.A.
29.7
N.A.
Protein Similarity:
100
98.1
100
100
N.A.
99.4
99.2
N.A.
82.8
38.5
91.5
89.6
N.A.
77.3
N.A.
39.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
6.6
93.3
93.3
N.A.
73.3
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
20
100
100
N.A.
86.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
42.7
52.1
Protein Similarity:
N.A.
N.A.
N.A.
40.8
57.6
64.7
P-Site Identity:
N.A.
N.A.
N.A.
0
60
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
0
73.3
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
0
0
7
7
0
7
0
7
80
14
% A
% Cys:
0
0
0
0
0
74
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
7
0
14
7
0
% D
% Glu:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% E
% Phe:
0
0
7
0
0
0
7
0
67
14
7
0
0
0
0
% F
% Gly:
7
7
0
0
74
7
7
0
7
0
0
0
7
0
14
% G
% His:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
14
7
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% K
% Leu:
0
14
7
0
0
7
0
7
0
7
0
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
80
0
0
7
0
7
0
7
0
0
40
0
7
0
0
% N
% Pro:
7
0
0
7
7
0
0
0
0
7
0
0
54
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% Q
% Arg:
0
0
0
80
0
0
7
0
0
0
0
0
7
7
0
% R
% Ser:
0
14
7
7
0
0
74
0
7
0
27
0
7
0
0
% S
% Thr:
0
54
0
0
0
0
7
0
0
0
7
7
0
0
0
% T
% Val:
0
0
74
0
0
0
0
0
0
0
0
7
0
0
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
74
7
60
7
74
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _