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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3CB
All Species:
43.64
Human Site:
Y122
Identified Species:
68.57
UniProt:
P16298
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16298
NP_001135826.1
524
59024
Y122
G
S
P
A
N
T
R
Y
L
F
L
G
D
Y
V
Chimpanzee
Pan troglodytes
XP_001142700
534
60207
Y122
G
S
P
A
N
T
R
Y
L
F
L
G
D
Y
V
Rhesus Macaque
Macaca mulatta
XP_001101616
524
59006
Y122
G
S
P
A
N
T
R
Y
L
F
L
G
D
Y
V
Dog
Lupus familis
XP_850935
524
59010
Y122
G
S
P
A
N
T
R
Y
L
F
L
G
D
Y
V
Cat
Felis silvestris
Mouse
Mus musculus
P48453
525
59155
Y122
G
S
P
A
N
T
R
Y
L
F
L
G
D
Y
V
Rat
Rattus norvegicus
P20651
525
59095
Y122
G
S
P
A
N
T
R
Y
L
F
L
G
D
Y
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505489
437
49430
R69
P
S
T
L
F
L
L
R
G
N
H
E
C
R
H
Chicken
Gallus gallus
P48463
309
35545
Frog
Xenopus laevis
NP_001080813
518
58366
Y113
G
S
P
A
N
T
R
Y
L
F
L
G
D
Y
V
Zebra Danio
Brachydanio rerio
NP_001017856
511
57796
Y102
G
S
P
A
T
T
R
Y
L
F
L
G
D
Y
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27889
570
63082
Y179
G
S
P
A
S
T
K
Y
L
F
L
G
D
Y
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTT8
321
36288
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48486
322
36548
Baker's Yeast
Sacchar. cerevisiae
P14747
604
68509
Y167
G
D
P
A
T
T
S
Y
L
F
L
G
D
Y
V
Red Bread Mold
Neurospora crassa
Q05681
558
63895
Y151
G
D
P
A
E
T
R
Y
L
F
L
G
D
Y
V
Conservation
Percent
Protein Identity:
100
98.1
99.6
99.6
N.A.
99
98.8
N.A.
81.8
27.6
81.8
81.4
N.A.
69.4
N.A.
29.7
N.A.
Protein Similarity:
100
98.1
100
100
N.A.
99.4
99.2
N.A.
82.8
38.5
91.5
89.6
N.A.
77.3
N.A.
39.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
0
100
93.3
N.A.
86.6
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
0
100
93.3
N.A.
100
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
42.7
52.1
Protein Similarity:
N.A.
N.A.
N.A.
40.8
57.6
64.7
P-Site Identity:
N.A.
N.A.
N.A.
0
80
86.6
P-Site Similarity:
N.A.
N.A.
N.A.
0
80
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
74
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
14
0
0
0
0
0
0
0
0
0
0
74
0
0
% D
% Glu:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
0
0
74
0
0
0
0
0
% F
% Gly:
74
0
0
0
0
0
0
0
7
0
0
74
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
7
0
7
7
0
74
0
74
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
47
0
0
0
0
7
0
0
0
0
0
% N
% Pro:
7
0
74
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
60
7
0
0
0
0
0
7
0
% R
% Ser:
0
67
0
0
7
0
7
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
7
0
14
74
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
74
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
74
0
0
0
0
0
74
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _