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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3CB
All Species:
31.82
Human Site:
T431
Identified Species:
50
UniProt:
P16298
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16298
NP_001135826.1
524
59024
T431
E
E
S
E
S
V
L
T
L
K
G
L
T
P
T
Chimpanzee
Pan troglodytes
XP_001142700
534
60207
T441
E
E
S
E
S
V
L
T
L
K
G
L
T
P
T
Rhesus Macaque
Macaca mulatta
XP_001101616
524
59006
T431
E
E
S
E
S
V
L
T
L
K
G
L
T
P
T
Dog
Lupus familis
XP_850935
524
59010
T431
E
E
S
E
S
V
L
T
L
K
G
L
T
P
T
Cat
Felis silvestris
Mouse
Mus musculus
P48453
525
59155
T432
E
E
S
E
S
V
L
T
L
K
G
L
T
P
T
Rat
Rattus norvegicus
P20651
525
59095
T432
E
E
S
E
S
V
L
T
L
K
G
L
T
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505489
437
49430
V357
T
G
M
L
P
S
G
V
L
A
G
G
R
Q
T
Chicken
Gallus gallus
P48463
309
35545
H230
D
I
S
E
T
F
N
H
A
N
G
L
T
L
V
Frog
Xenopus laevis
NP_001080813
518
58366
T422
E
E
S
E
S
V
L
T
L
K
G
L
T
P
T
Zebra Danio
Brachydanio rerio
NP_001017856
511
57796
T412
E
E
S
E
N
V
L
T
L
K
G
L
T
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27889
570
63082
Q490
E
E
S
E
S
V
L
Q
L
K
G
L
T
P
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTT8
321
36288
F242
L
F
C
E
N
N
D
F
L
R
I
C
R
A
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48486
322
36548
R243
H
D
L
D
L
I
C
R
A
H
Q
V
V
E
D
Baker's Yeast
Sacchar. cerevisiae
P14747
604
68509
L522
V
S
R
M
Y
S
V
L
R
E
E
T
N
K
V
Red Bread Mold
Neurospora crassa
Q05681
558
63895
E475
E
E
S
E
R
V
T
E
L
K
T
V
S
G
G
Conservation
Percent
Protein Identity:
100
98.1
99.6
99.6
N.A.
99
98.8
N.A.
81.8
27.6
81.8
81.4
N.A.
69.4
N.A.
29.7
N.A.
Protein Similarity:
100
98.1
100
100
N.A.
99.4
99.2
N.A.
82.8
38.5
91.5
89.6
N.A.
77.3
N.A.
39.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
20
33.3
100
93.3
N.A.
93.3
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
46.6
100
100
N.A.
93.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
42.7
52.1
Protein Similarity:
N.A.
N.A.
N.A.
40.8
57.6
64.7
P-Site Identity:
N.A.
N.A.
N.A.
0
0
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
14
7
0
0
0
7
0
% A
% Cys:
0
0
7
0
0
0
7
0
0
0
0
7
0
0
0
% C
% Asp:
7
7
0
7
0
0
7
0
0
0
0
0
0
0
7
% D
% Glu:
67
67
0
80
0
0
0
7
0
7
7
0
0
7
0
% E
% Phe:
0
7
0
0
0
7
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
0
7
0
0
0
74
7
0
7
7
% G
% His:
7
0
0
0
0
0
0
7
0
7
0
0
0
0
7
% H
% Ile:
0
7
0
0
0
7
0
0
0
0
7
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
67
0
0
0
7
0
% K
% Leu:
7
0
7
7
7
0
60
7
80
0
0
67
0
7
0
% L
% Met:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
14
7
7
0
0
7
0
0
7
0
0
% N
% Pro:
0
0
0
0
7
0
0
0
0
0
0
0
0
60
0
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
7
0
0
7
0
% Q
% Arg:
0
0
7
0
7
0
0
7
7
7
0
0
14
0
0
% R
% Ser:
0
7
74
0
54
14
0
0
0
0
0
0
7
0
0
% S
% Thr:
7
0
0
0
7
0
7
54
0
0
7
7
67
0
67
% T
% Val:
7
0
0
0
0
67
7
7
0
0
0
14
7
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _