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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3CB
All Species:
41.52
Human Site:
S426
Identified Species:
65.24
UniProt:
P16298
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16298
NP_001135826.1
524
59024
S426
F
S
V
L
R
E
E
S
E
S
V
L
T
L
K
Chimpanzee
Pan troglodytes
XP_001142700
534
60207
S436
F
S
V
L
R
E
E
S
E
S
V
L
T
L
K
Rhesus Macaque
Macaca mulatta
XP_001101616
524
59006
S426
F
S
V
L
R
E
E
S
E
S
V
L
T
L
K
Dog
Lupus familis
XP_850935
524
59010
S426
F
S
V
L
R
E
E
S
E
S
V
L
T
L
K
Cat
Felis silvestris
Mouse
Mus musculus
P48453
525
59155
S427
F
S
V
L
R
E
E
S
E
S
V
L
T
L
K
Rat
Rattus norvegicus
P20651
525
59095
S427
F
S
V
L
R
E
E
S
E
S
V
L
T
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505489
437
49430
M352
K
G
L
T
P
T
G
M
L
P
S
G
V
L
A
Chicken
Gallus gallus
P48463
309
35545
S225
Y
T
F
G
Q
D
I
S
E
T
F
N
H
A
N
Frog
Xenopus laevis
NP_001080813
518
58366
S417
F
S
V
L
R
E
E
S
E
S
V
L
T
L
K
Zebra Danio
Brachydanio rerio
NP_001017856
511
57796
S407
F
S
V
L
R
E
E
S
E
N
V
L
T
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27889
570
63082
S485
F
S
V
L
R
E
E
S
E
S
V
L
Q
L
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTT8
321
36288
C237
G
D
A
A
E
L
F
C
E
N
N
D
F
L
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48486
322
36548
L238
E
F
L
Q
T
H
D
L
D
L
I
C
R
A
H
Baker's Yeast
Sacchar. cerevisiae
P14747
604
68509
R517
L
A
V
A
K
V
S
R
M
Y
S
V
L
R
E
Red Bread Mold
Neurospora crassa
Q05681
558
63895
S470
F
Q
V
L
R
E
E
S
E
R
V
T
E
L
K
Conservation
Percent
Protein Identity:
100
98.1
99.6
99.6
N.A.
99
98.8
N.A.
81.8
27.6
81.8
81.4
N.A.
69.4
N.A.
29.7
N.A.
Protein Similarity:
100
98.1
100
100
N.A.
99.4
99.2
N.A.
82.8
38.5
91.5
89.6
N.A.
77.3
N.A.
39.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
13.3
100
93.3
N.A.
93.3
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
46.6
100
100
N.A.
93.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
42.7
52.1
Protein Similarity:
N.A.
N.A.
N.A.
40.8
57.6
64.7
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
73.3
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
14
0
0
0
0
0
0
0
0
0
14
7
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% C
% Asp:
0
7
0
0
0
7
7
0
7
0
0
7
0
0
0
% D
% Glu:
7
0
0
0
7
67
67
0
80
0
0
0
7
0
7
% E
% Phe:
67
7
7
0
0
0
7
0
0
0
7
0
7
0
0
% F
% Gly:
7
7
0
7
0
0
7
0
0
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
7
0
7
% H
% Ile:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% I
% Lys:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
67
% K
% Leu:
7
0
14
67
0
7
0
7
7
7
0
60
7
80
0
% L
% Met:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
14
7
7
0
0
7
% N
% Pro:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
0
7
0
7
7
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
0
0
67
0
0
7
0
7
0
0
7
7
7
% R
% Ser:
0
60
0
0
0
0
7
74
0
54
14
0
0
0
0
% S
% Thr:
0
7
0
7
7
7
0
0
0
7
0
7
54
0
0
% T
% Val:
0
0
74
0
0
7
0
0
0
0
67
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _