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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3CB
All Species:
35.76
Human Site:
S242
Identified Species:
56.19
UniProt:
P16298
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16298
NP_001135826.1
524
59024
S242
P
M
C
D
L
L
W
S
D
P
S
E
D
F
G
Chimpanzee
Pan troglodytes
XP_001142700
534
60207
S242
P
M
C
D
L
L
W
S
D
P
S
E
D
F
G
Rhesus Macaque
Macaca mulatta
XP_001101616
524
59006
S242
P
M
C
D
L
L
W
S
D
P
S
E
D
F
G
Dog
Lupus familis
XP_850935
524
59010
S242
P
M
C
D
L
L
W
S
D
P
S
E
D
F
G
Cat
Felis silvestris
Mouse
Mus musculus
P48453
525
59155
S242
P
M
C
D
L
L
W
S
D
P
S
E
D
F
G
Rat
Rattus norvegicus
P20651
525
59095
S242
P
M
C
D
L
L
W
S
D
P
S
E
D
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505489
437
49430
G176
F
S
H
N
T
V
R
G
C
S
Y
F
Y
S
Y
Chicken
Gallus gallus
P48463
309
35545
R49
E
S
N
V
Q
E
V
R
C
P
V
T
V
C
G
Frog
Xenopus laevis
NP_001080813
518
58366
S233
P
M
C
D
I
L
W
S
D
P
L
E
D
Y
G
Zebra Danio
Brachydanio rerio
NP_001017856
511
57796
S222
P
M
C
D
L
L
W
S
D
P
L
E
D
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27889
570
63082
S299
P
M
C
D
L
L
W
S
D
P
L
E
D
F
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTT8
321
36288
I61
V
I
D
T
P
V
T
I
C
G
D
I
H
G
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48486
322
36548
V62
P
I
K
I
C
G
D
V
H
G
Q
F
P
D
L
Baker's Yeast
Sacchar. cerevisiae
P14747
604
68509
T311
E
D
I
V
N
S
K
T
M
V
P
H
H
G
K
Red Bread Mold
Neurospora crassa
Q05681
558
63895
A271
L
M
C
D
I
L
W
A
D
P
L
E
D
F
G
Conservation
Percent
Protein Identity:
100
98.1
99.6
99.6
N.A.
99
98.8
N.A.
81.8
27.6
81.8
81.4
N.A.
69.4
N.A.
29.7
N.A.
Protein Similarity:
100
98.1
100
100
N.A.
99.4
99.2
N.A.
82.8
38.5
91.5
89.6
N.A.
77.3
N.A.
39.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
13.3
80
93.3
N.A.
93.3
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
13.3
93.3
93.3
N.A.
93.3
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
42.7
52.1
Protein Similarity:
N.A.
N.A.
N.A.
40.8
57.6
64.7
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
73.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
67
0
7
0
0
0
20
0
0
0
0
7
0
% C
% Asp:
0
7
7
67
0
0
7
0
67
0
7
0
67
7
0
% D
% Glu:
14
0
0
0
0
7
0
0
0
0
0
67
0
0
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
14
0
60
0
% F
% Gly:
0
0
0
0
0
7
0
7
0
14
0
0
0
14
74
% G
% His:
0
0
7
0
0
0
0
0
7
0
0
7
14
0
0
% H
% Ile:
0
14
7
7
14
0
0
7
0
0
0
7
0
0
0
% I
% Lys:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
7
% K
% Leu:
7
0
0
0
54
67
0
0
0
0
27
0
0
0
7
% L
% Met:
0
67
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
7
7
7
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
67
0
0
0
7
0
0
0
0
74
7
0
7
0
0
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
7
% Q
% Arg:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% R
% Ser:
0
14
0
0
0
7
0
60
0
7
40
0
0
7
0
% S
% Thr:
0
0
0
7
7
0
7
7
0
0
0
7
0
0
0
% T
% Val:
7
0
0
14
0
14
7
7
0
7
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
7
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _