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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A16
All Species:
23.33
Human Site:
Y291
Identified Species:
34.22
UniProt:
P16260
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16260
NP_689920.1
332
36224
Y291
R
D
T
M
K
Y
V
Y
G
H
H
G
I
R
K
Chimpanzee
Pan troglodytes
XP_001168284
332
36249
Y291
R
D
T
M
K
Y
V
Y
G
H
H
G
I
R
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546134
332
36141
Y291
W
E
T
M
K
Y
V
Y
G
H
H
G
I
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0K5
332
36201
Y291
R
E
T
M
K
Y
V
Y
G
Q
H
G
I
R
R
Rat
Rattus norvegicus
P16261
322
35038
L284
L
P
E
F
E
K
C
L
T
M
R
E
T
M
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520566
324
35638
Y283
L
K
T
L
K
Y
V
Y
G
H
H
G
I
R
R
Chicken
Gallus gallus
XP_421570
320
35184
Y279
V
Q
T
L
K
Y
V
Y
Q
Q
H
G
I
R
R
Frog
Xenopus laevis
Q5PQ27
327
36043
Y288
E
G
F
I
R
G
L
Y
K
G
L
S
M
N
W
Zebra Danio
Brachydanio rerio
Q0P483
321
35318
V277
L
G
T
M
R
E
I
V
A
E
E
G
I
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624199
316
35726
K277
Y
K
E
N
G
I
I
K
G
L
Y
R
G
M
S
Nematode Worm
Caenorhab. elegans
Q20799
588
66319
R503
E
G
V
T
G
F
Y
R
G
I
T
P
N
F
L
Sea Urchin
Strong. purpuratus
XP_789697
271
30376
G233
G
F
L
G
L
Y
R
G
L
S
I
N
Y
I
R
Poplar Tree
Populus trichocarpa
XP_002308549
340
37252
L301
W
K
Q
L
F
A
G
L
S
I
N
Y
I
K
I
Maize
Zea mays
P29518
436
46609
Y385
K
E
G
A
G
G
L
Y
R
G
L
G
P
S
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172908
331
36237
A293
Q
G
W
K
Q
L
F
A
G
L
S
I
N
Y
I
Baker's Yeast
Sacchar. cerevisiae
P38702
357
40807
H315
Q
S
I
S
E
I
A
H
I
I
F
K
E
R
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
96
N.A.
92.7
88.8
N.A.
82.5
81
37
38.2
N.A.
N.A.
50.2
20.2
39.7
Protein Similarity:
100
99.6
N.A.
98.1
N.A.
96.6
92.7
N.A.
87.9
86.7
54.2
53.9
N.A.
N.A.
62
31.6
53.6
P-Site Identity:
100
100
N.A.
80
N.A.
80
6.6
N.A.
73.3
60
6.6
26.6
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
13.3
N.A.
86.6
73.3
33.3
46.6
N.A.
N.A.
20
13.3
13.3
Percent
Protein Identity:
34.4
21.7
N.A.
37.9
37.5
N.A.
Protein Similarity:
54.4
34.8
N.A.
53.6
55.1
N.A.
P-Site Identity:
6.6
13.3
N.A.
6.6
6.6
N.A.
P-Site Similarity:
26.6
33.3
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
7
7
7
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% C
% Asp:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
13
19
13
0
13
7
0
0
0
7
7
7
7
0
0
% E
% Phe:
0
7
7
7
7
7
7
0
0
0
7
0
0
7
0
% F
% Gly:
7
25
7
7
19
13
7
7
50
13
0
50
7
0
7
% G
% His:
0
0
0
0
0
0
0
7
0
25
38
0
0
0
0
% H
% Ile:
0
0
7
7
0
13
13
0
7
19
7
7
50
7
13
% I
% Lys:
7
19
0
7
38
7
0
7
7
0
0
7
0
7
19
% K
% Leu:
19
0
7
19
7
7
13
13
7
13
13
0
0
0
7
% L
% Met:
0
0
0
32
0
0
0
0
0
7
0
0
7
13
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
7
7
13
7
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
7
7
0
0
% P
% Gln:
13
7
7
0
7
0
0
0
7
13
0
0
0
0
0
% Q
% Arg:
19
0
0
0
13
0
7
7
7
0
7
7
0
44
38
% R
% Ser:
0
7
0
7
0
0
0
0
7
7
7
7
0
7
7
% S
% Thr:
0
0
44
7
0
0
0
0
7
0
7
0
7
0
0
% T
% Val:
7
0
7
0
0
0
38
7
0
0
0
0
0
7
0
% V
% Trp:
13
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
7
0
0
0
0
44
7
50
0
0
7
7
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _