KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACAN
All Species:
3.03
Human Site:
T2057
Identified Species:
8.33
UniProt:
P16112
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16112
NP_037359
2415
250193
T2057
P
E
V
S
G
E
S
T
T
T
S
D
V
G
T
Chimpanzee
Pan troglodytes
Q5IS41
1321
142848
L995
A
S
G
E
E
P
A
L
P
G
T
P
M
K
A
Rhesus Macaque
Macaca mulatta
XP_001091462
1544
155715
S1218
A
S
A
A
P
E
T
S
G
E
D
S
G
S
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q61282
2132
221991
E1800
T
F
Q
E
G
T
R
E
G
S
A
A
P
E
V
Rat
Rattus norvegicus
P07897
2124
221100
A1796
G
T
R
E
G
S
A
A
P
E
V
S
G
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521630
2020
206538
N1694
E
V
S
G
E
T
S
N
V
G
L
E
S
S
G
Chicken
Gallus gallus
P07898
2109
223475
V1783
E
T
S
V
P
D
A
V
I
S
T
S
A
P
D
Frog
Xenopus laevis
NP_001082106
1152
126842
S826
V
Q
I
S
Q
L
K
S
S
S
V
I
S
T
E
Zebra Danio
Brachydanio rerio
XP_686182
1559
166402
E1233
L
G
P
Y
L
K
P
E
E
I
I
N
N
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.5
55.1
N.A.
N.A.
69.1
68.7
N.A.
49.1
47.1
24.1
36.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
35.4
58.2
N.A.
N.A.
75.4
74.6
N.A.
58.5
59.4
34.9
45.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
6.6
N.A.
N.A.
6.6
6.6
N.A.
6.6
0
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
26.6
N.A.
N.A.
20
20
N.A.
13.3
26.6
40
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
12
12
0
0
34
12
0
0
12
12
12
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
0
0
0
12
12
0
0
23
% D
% Glu:
23
12
0
34
23
23
0
23
12
23
0
12
0
23
12
% E
% Phe:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
12
12
12
34
0
0
0
23
23
0
0
23
12
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
0
0
0
12
12
12
12
0
0
0
% I
% Lys:
0
0
0
0
0
12
12
0
0
0
0
0
0
12
0
% K
% Leu:
12
0
0
0
12
12
0
12
0
0
12
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
12
12
0
0
% N
% Pro:
12
0
12
0
23
12
12
0
23
0
0
12
12
12
12
% P
% Gln:
0
12
12
0
12
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
12
0
0
0
12
0
0
0
0
0
0
0
0
% R
% Ser:
0
23
23
23
0
12
23
23
12
34
12
34
23
23
12
% S
% Thr:
12
23
0
0
0
23
12
12
12
12
23
0
0
12
12
% T
% Val:
12
12
12
12
0
0
0
12
12
0
23
0
12
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _